ID   YDHK_ECO57              Reviewed;         670 AA.
AC   Q8X638;
DT   16-APR-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Uncharacterized transporter YdhK;
GN   Name=ydhK; OrderedLocusNames=Z2660, ECs2354;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the aromatic acid exporter ArAE (TC 2.A.85)
CC       family. {ECO:0000305}.
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DR   EMBL; AE005174; AAG56634.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB35777.1; -; Genomic_DNA.
DR   PIR; B99923; B99923.
DR   PIR; F85771; F85771.
DR   RefSeq; NP_310381.1; NC_002695.1.
DR   RefSeq; WP_000994327.1; NZ_SEKU01000008.1.
DR   AlphaFoldDB; Q8X638; -.
DR   STRING; 155864.EDL933_2601; -.
DR   TCDB; 2.A.85.1.6; the aromatic acid exporter (arae) family.
DR   EnsemblBacteria; AAG56634; AAG56634; Z2660.
DR   EnsemblBacteria; BAB35777; BAB35777; ECs_2354.
DR   GeneID; 912808; -.
DR   KEGG; ece:Z2660; -.
DR   KEGG; ecs:ECs_2354; -.
DR   PATRIC; fig|386585.9.peg.2463; -.
DR   eggNOG; COG1289; Bacteria.
DR   HOGENOM; CLU_013927_3_0_6; -.
DR   OMA; LNDPWLF; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR006726; PHBA_efflux_AaeB/fusaric-R.
DR   Pfam; PF04632; FUSC; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..670
FT                   /note="Uncharacterized transporter YdhK"
FT                   /id="PRO_0000210094"
FT   TRANSMEM        23..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        47..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        76..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        118..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        153..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        381..403
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        410..432
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        437..454
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        461..483
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        493..510
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   670 AA;  75308 MW;  C11BC1312A40C385 CRC64;
     MNASSWSLRN LPWFRATLAQ WRYALRNTIA MCLALTVAYY LNLDEPYWAM TSAAVVSFPT
     VGGVISKSLG RIAGSLLGAI AALLLAGHTL NEPWFFLLSM SAWLGFCTWA CAHFTNNVAY
     AFQLAGYTAA IIAFPMVNIT EASQLWDIAQ ARVCEVIVGI LCGGMMMMIL PSSSDATALL
     TALKNMHARL LEHASLLWQP ETTDAIRAAH EGVIGQILTM NLLRIQAFWS HYRFRQQNAR
     LNALLHQQLR MTSVISSLRR MLLNWPSPPG ATREILEQLL TALASSQTDV YTVARIIAPL
     RPTNVADYRH VAFWQRLRYF CRLYLQSSQE LHRLQSDVDD HARLPRTSGL ARHTDNAEAM
     WSGLRTFCTL MMIGAWSIAS QWDAGANALT LAAISCVLYS AVAAPFKSLS LLMRTLVLLS
     LFSFVVKFGL MVQISDLWQF LLFLFPLLAT MQLLKLQMPK FAALWGQLIV FMGSFIAVTN
     PPVYNFADFL NDNLAKIVGV ALAWLAFAIL RPGSDARKSR RHIRALRRDF VDQLSRHPTL
     SESEFESLTY HHVSQLSNSQ DALARRWLLR WGIVLLNCSH VVWQLRDWES RSDPLSRVRD
     NCISLLRGVM SERGVQQKSL AATLEELQRI CDSLARHHQP AARELAAIVW RLYCSLSQLE
     QAPPQGTLAS