ID   YDHK_ECOLI              Reviewed;         670 AA.
AC   P76186; P76894;
DT   16-APR-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 132.
DE   RecName: Full=Uncharacterized transporter YdhK;
GN   Name=ydhK; OrderedLocusNames=b1645, JW1637;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 1-169.
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA   Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA   Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA   Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA   Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA   Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA   Wada C., Yamamoto Y., Horiuchi T.;
RT   "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 28.0-40.1 min region on the linkage map.";
RL   DNA Res. 3:363-377(1996).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the aromatic acid exporter ArAE (TC 2.A.85)
CC       family. {ECO:0000305}.
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DR   EMBL; U00096; AAC74717.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA15405.1; -; Genomic_DNA.
DR   PIR; G64921; G64921.
DR   RefSeq; NP_416162.1; NC_000913.3.
DR   RefSeq; WP_000994333.1; NZ_STEB01000003.1.
DR   AlphaFoldDB; P76186; -.
DR   BioGRID; 4263048; 183.
DR   IntAct; P76186; 5.
DR   STRING; 511145.b1645; -.
DR   PaxDb; P76186; -.
DR   PRIDE; P76186; -.
DR   EnsemblBacteria; AAC74717; AAC74717; b1645.
DR   EnsemblBacteria; BAA15405; BAA15405; BAA15405.
DR   GeneID; 946528; -.
DR   KEGG; ecj:JW1637; -.
DR   KEGG; eco:b1645; -.
DR   PATRIC; fig|1411691.4.peg.614; -.
DR   EchoBASE; EB3703; -.
DR   eggNOG; COG1289; Bacteria.
DR   InParanoid; P76186; -.
DR   OMA; LNDPWLF; -.
DR   PhylomeDB; P76186; -.
DR   BioCyc; EcoCyc:G6885-MON; -.
DR   PRO; PR:P76186; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR   InterPro; IPR006726; PHBA_efflux_AaeB/fusaric-R.
DR   Pfam; PF04632; FUSC; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..670
FT                   /note="Uncharacterized transporter YdhK"
FT                   /id="PRO_0000210093"
FT   TRANSMEM        23..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        47..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        76..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        118..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        153..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        381..403
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        410..432
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        437..454
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        461..483
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        493..510
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   670 AA;  75267 MW;  285C136651DD5EFA CRC64;
     MNASSWSLRN LPWFRATLAQ WRYALRNTIA MCLALTVAYY LNLDEPYWAM TSAAVVSFPT
     VGGVISKSLG RIAGSLLGAI AALLLAGHTL NEPWFFLLSM SAWLGFCTWA CAHFTNNVAY
     AFQLAGYTAA IIAFPMVNIT EASQLWDIAQ ARVCEVIVGI LCGGMMMMIL PSSSDATALL
     TALKNMHARL LEHASLLWQP ETTDAIRAAH EGVIGQILTM NLLRIQAFWS HYRFRQQNAR
     LNALLHQQLR MTSVISSLRR MLLNWPSPPG ATREILEQLL TALASSQTDV YTVARIIAPL
     RPTNVADYRH VAFWQRLRYF CRLYLQSSQE LHRLQSGVDD HTRLPRTSGL ARHTDNAEAM
     WSGLRTFCTL MMIGAWSIAS QWDAGANALT LAAISCVLYS AVAAPFKSLS LLMRTLVLLS
     LFSFVVKFGL MVQISDLWQF LLFLFPLLAT MQLLKLQMPK FAALWGQLIV FMGSFIAVTN
     PPVYDFADFL NDNLAKIVGV ALAWLAFAIL RPGSDARKSR RHIRALRRDF VDQLSRHPTL
     SESEFESLTY HHVSQLSNSQ DALARRWLLR WGVVLLNCSH VVWQLRDWES RSDPLSRVRD
     NCISLLRGVM SERGVQQKSL AATLEELQRI CDSLARHHQP AARELAAIVW RLYCSLSQLE
     QAPPQGTLAS