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YDHK_SALTI
ID   YDHK_SALTI              Reviewed;         679 AA.
AC   Q8Z6P7;
DT   16-APR-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=Uncharacterized transporter YdhK;
GN   Name=ydhK; OrderedLocusNames=STY1681, t1309;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the aromatic acid exporter ArAE (TC 2.A.85)
CC       family. {ECO:0000305}.
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DR   EMBL; AL513382; CAD01926.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO68959.1; -; Genomic_DNA.
DR   RefSeq; NP_456089.1; NC_003198.1.
DR   RefSeq; WP_000777620.1; NZ_WSUR01000011.1.
DR   AlphaFoldDB; Q8Z6P7; -.
DR   STRING; 220341.16502768; -.
DR   EnsemblBacteria; AAO68959; AAO68959; t1309.
DR   KEGG; stt:t1309; -.
DR   KEGG; sty:STY1681; -.
DR   PATRIC; fig|220341.7.peg.1691; -.
DR   eggNOG; COG1289; Bacteria.
DR   HOGENOM; CLU_013927_3_0_6; -.
DR   OMA; LNDPWLF; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR006726; PHBA_efflux_AaeB/fusaric-R.
DR   Pfam; PF04632; FUSC; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..679
FT                   /note="Uncharacterized transporter YdhK"
FT                   /id="PRO_0000210095"
FT   TRANSMEM        23..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        46..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        72..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        94..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        120..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        157..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        362..381
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        385..404
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        411..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        438..455
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        462..481
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        496..515
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   679 AA;  76490 MW;  DFFDB09182EAF484 CRC64;
     MKLSLPALRN TPWFKATSGQ WRYALRNTIA MCLALTFAYY LNLDEPYWAM TSAAVVSFPT
     VGGVISKSLG RIAGSLLGAT AALIIAGHTL NEPWLFLFSM AAWIGFCTWA CAHFTNNAAY
     AFQLSGYTAA IIAFPMVNIV EITQLWDIAQ ARVCEVIVGI LCGGMMMMIL PSTSDGTALL
     TALKNMHARL LEHASLLWQP ETTDAIRSAH EGVIGQILTM NLLRIQAFWS HYRFRRQNAL
     LNALLHQQLR LTSVISSLRR MLLNWPTPPE NSREVIEQLL AELAKPRADS YTVARIIAPL
     CPQDEQDYRH LAFWQRLRYF CQLYLRSSRQ LYLIESGAPV DQIHIRRTPG LARHTDNAEA
     IWSGVRTFCT LTVIGAWSIG VQWESGPGAL TLAAISCVLY SIVATPFKSL SLLMRTLVLL
     SLFSFVVKFG LMVQITDLWQ FLLFLFPLFV TMQLLKLQMP KLAGLWGQLI VFMGSFIAVT
     NPPVYDFADF LNDNTAKIVG VAISWLAFAI LRPGSDAVKS RRHIRALRRD FVDQLSRHPS
     HSESEFESLT YHHVSQLSNS QDALARRWLL RWGVVLLNCS HVVWQLRAWE SRSDPLSRVR
     DICISLLRDV MSERDVQQRP LAVTLQELQR ICDTLAHHHQ PAAHELAAII WRLHCSLSQL
     EQAPAQGTLS PGYLMTPQA
 
 
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