YDHK_SALTY
ID YDHK_SALTY Reviewed; 679 AA.
AC Q8ZPN4;
DT 16-APR-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=Uncharacterized transporter YdhK;
GN Name=ydhK; OrderedLocusNames=STM1441;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the aromatic acid exporter ArAE (TC 2.A.85)
CC family. {ECO:0000305}.
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DR EMBL; AE006468; AAL20363.1; -; Genomic_DNA.
DR RefSeq; NP_460404.1; NC_003197.2.
DR RefSeq; WP_000777608.1; NC_003197.2.
DR AlphaFoldDB; Q8ZPN4; -.
DR STRING; 99287.STM1441; -.
DR TCDB; 2.A.85.1.5; the aromatic acid exporter (arae) family.
DR PaxDb; Q8ZPN4; -.
DR EnsemblBacteria; AAL20363; AAL20363; STM1441.
DR GeneID; 1252959; -.
DR KEGG; stm:STM1441; -.
DR PATRIC; fig|99287.12.peg.1524; -.
DR HOGENOM; CLU_013927_3_0_6; -.
DR OMA; LNDPWLF; -.
DR PhylomeDB; Q8ZPN4; -.
DR BioCyc; SENT99287:STM1441-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR InterPro; IPR006726; PHBA_efflux_AaeB/fusaric-R.
DR Pfam; PF04632; FUSC; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..679
FT /note="Uncharacterized transporter YdhK"
FT /id="PRO_0000210096"
FT TRANSMEM 23..41
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 46..65
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 72..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 94..113
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 120..142
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 157..179
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 362..381
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 385..404
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 411..433
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 438..455
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 462..481
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 496..515
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 679 AA; 76474 MW; A99161B73EC01100 CRC64;
MKLSLPALRN TPWFKATSGQ WRYALRNTIA MCLALTFAYY LNLDEPYWAM TSAAVVSFPT
VGGVISKSLG RIAGSLLGAT AALIIAGHTL NEPWLFLFSM AAWIGFCTWA CAHFTNNAAY
AFQLSGYTAA IIAFPMVNIV EITQLWDIAQ ARVCEVIVGI LCGGMMMMIL PSTSDGTALL
TAFKNMHARL LEHASLLWQP ETTDAIRSAH EGVIGQILTM NLLRIQAFWS HYRFRRQNAL
LNALLHQQLR LTSVISSLRR MLLNWPTPPE NSREVIEQLL AELAKPRADS YTVAQIIAPL
RPQDEQDYRH LAFWQRLRYF CQLYLRSSRQ LYLIESGAPV DQIHIRRTPG LARHTDNAEA
IWSGVRTFCT LTVIGAWSIG AQWESGPGAL TLAAISCVLY SIVATPFKSL SLLMRTLVLL
SLFSFVVKFG LMVQITDLWQ FLLFLFPLFV TMQLLKLQMP KLAGLWGQLI VFMGSFIAVT
NPPVYDFADF LNDNTAKIVG VAISWLAFAI LRPGSDAVKS RRHIRALRRD FVDQLSRHPS
HNESEFESLT YHHVSQLSNS QDALARRWLL RWGVVLLNCS HVVWQLRAWE SRSDPLSRVR
DICISLLRDV MSERGVQQRP LAVTLQELQR ICDTLAHHHQ PAAHELAAII WRLHCSLSQL
EQAPAQGTLA PGYLMTPQA