YDIV_SALCH
ID YDIV_SALCH Reviewed; 237 AA.
AC Q57PU2;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 10-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 67.
DE RecName: Full=Anti-FlhC(2)FlhD(4) factor YdiV;
GN Name=ydiV; OrderedLocusNames=SCH_1363;
OS Salmonella choleraesuis (strain SC-B67).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=321314;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC-B67;
RX PubMed=15781495; DOI=10.1093/nar/gki297;
RA Chiu C.-H., Tang P., Chu C., Hu S., Bao Q., Yu J., Chou Y.-Y., Wang H.-S.,
RA Lee Y.-S.;
RT "The genome sequence of Salmonella enterica serovar Choleraesuis, a highly
RT invasive and resistant zoonotic pathogen.";
RL Nucleic Acids Res. 33:1690-1698(2005).
CC -!- FUNCTION: Acts as an anti-FlhC(2)FlhD(4) factor by binding to FlhD,
CC decreasing its ability to bind DNA, and thus negatively regulates
CC expression of flagellar class II operons, decreasing motility in
CC nutrient-poor medium. Required for resistance to host phagocyte oxidase
CC (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with FlhD in the FlhC(2)FlhD(4) heterohexamer,
CC inhibiting its ability to activate transcription. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the YdiV family. {ECO:0000305}.
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DR EMBL; AE017220; AAX65269.1; -; Genomic_DNA.
DR RefSeq; WP_001539882.1; NC_006905.1.
DR AlphaFoldDB; Q57PU2; -.
DR SMR; Q57PU2; -.
DR EnsemblBacteria; AAX65269; AAX65269; SCH_1363.
DR KEGG; sec:SCH_1363; -.
DR HOGENOM; CLU_089254_1_1_6; -.
DR OMA; SFEPFMR; -.
DR Proteomes; UP000000538; Chromosome.
DR Gene3D; 3.20.20.450; -; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR Pfam; PF00563; EAL; 1.
DR SUPFAM; SSF141868; SSF141868; 1.
PE 3: Inferred from homology;
KW Repressor; Transcription; Transcription regulation; Virulence.
FT CHAIN 1..237
FT /note="Anti-FlhC(2)FlhD(4) factor YdiV"
FT /id="PRO_0000346866"
FT DOMAIN 1..237
FT /note="EAL"
SQ SEQUENCE 237 AA; 26412 MW; 6A3A81E2DEA4B530 CRC64;
MIASLDELYH SELFFLPVMD ENAWLVGLAI IATFAAEDGA VRMPTELVAP RLSVEEQYCL
FVEKLALLET CQHFFIQHKL IAWLNLPPAI SDLLLLDSEL FSRAARFPFL ELAINENYPG
LNQGKNNETL ANLAMHFPLM LANFGSGEAS TKAIFDGLFK RVMLDKNFIQ QRAEMISFEP
FMHAIVAQIS SSCESLMIAG IDTEAMFARA APLGFSAFQG GLWPPVPVSQ LIKLVQR