ID   YDIV_SALPB              Reviewed;         237 AA.
AC   A9N230;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Anti-FlhC(2)FlhD(4) factor YdiV;
GN   Name=ydiV; OrderedLocusNames=SPAB_01992;
OS   Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=1016998;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1250 / SPB7;
RG   The Salmonella enterica serovar Paratyphi B Genome Sequencing Project;
RA   McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA   Fulton R., Cordes M., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W.,
RA   Johnson M., Thiruvilangam P., Wilson R.;
RL   Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as an anti-FlhC(2)FlhD(4) factor by binding to FlhD,
CC       decreasing its ability to bind DNA, and thus negatively regulates
CC       expression of flagellar class II operons, decreasing motility in
CC       nutrient-poor medium. Required for resistance to host phagocyte oxidase
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with FlhD in the FlhC(2)FlhD(4) heterohexamer,
CC       inhibiting its ability to activate transcription. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the YdiV family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000886; ABX67379.1; -; Genomic_DNA.
DR   RefSeq; WP_000562006.1; NC_010102.1.
DR   AlphaFoldDB; A9N230; -.
DR   SMR; A9N230; -.
DR   KEGG; spq:SPAB_01992; -.
DR   PATRIC; fig|1016998.12.peg.1880; -.
DR   HOGENOM; CLU_089254_1_1_6; -.
DR   OMA; SFEPFMR; -.
DR   BioCyc; SENT1016998:SPAB_RS08125-MON; -.
DR   Proteomes; UP000008556; Chromosome.
DR   Gene3D; 3.20.20.450; -; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   Pfam; PF00563; EAL; 1.
DR   SUPFAM; SSF141868; SSF141868; 1.
PE   3: Inferred from homology;
KW   Repressor; Transcription; Transcription regulation; Virulence.
FT   CHAIN           1..237
FT                   /note="Anti-FlhC(2)FlhD(4) factor YdiV"
FT                   /id="PRO_0000346868"
FT   DOMAIN          1..237
FT                   /note="EAL"
SQ   SEQUENCE   237 AA;  26414 MW;  558A591D0845C895 CRC64;
     MIASLDELYH SELFFLPVMD ENARLVGLEI IATFAAEDGA VRMPTELVAP RLSVEEQYCL
     FVEKLALLET CQHFFIQHKL IAWLNLPPAI SDLLLLDSEL FSRAARFPFL ELAINENYPG
     LNQGKNNETL ANLAMHFPLM LANFGAGEAS TKAIFDGLFK RVMLDKNFIQ QRAEMISFEP
     FMHAIVAQIS SSCESLMIAG IDTEAMFARA APLGFSAFQG GLWPSVPVSQ LIKLVQR