YDJ8_SCHPO
ID YDJ8_SCHPO Reviewed; 364 AA.
AC P87056;
DT 04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 2.
DT 25-MAY-2022, entry version 106.
DE RecName: Full=Abhydrolase domain-containing protein C57A10.08c;
DE EC=3.-.-.-;
GN ORFNames=SPAC57A10.08c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1] {ECO:0000312|EMBL:CAB08171.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2] {ECO:0000305}
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000255};
CC Single-pass type II membrane protein {ECO:0000255,
CC ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. {ECO:0000255}.
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DR EMBL; CU329670; CAB08171.2; -; Genomic_DNA.
DR PIR; T38935; T38935.
DR RefSeq; NP_593313.1; NM_001018744.2.
DR AlphaFoldDB; P87056; -.
DR SMR; P87056; -.
DR BioGRID; 279277; 9.
DR STRING; 4896.SPAC57A10.08c.1; -.
DR ESTHER; schpo-C57A10.08C; AlphaBeta_hydrolase.
DR iPTMnet; P87056; -.
DR MaxQB; P87056; -.
DR PaxDb; P87056; -.
DR EnsemblFungi; SPAC57A10.08c.1; SPAC57A10.08c.1:pep; SPAC57A10.08c.
DR GeneID; 2542830; -.
DR KEGG; spo:SPAC57A10.08c; -.
DR PomBase; SPAC57A10.08c; -.
DR VEuPathDB; FungiDB:SPAC57A10.08c; -.
DR eggNOG; ENOG502SB79; Eukaryota.
DR HOGENOM; CLU_761078_0_0_1; -.
DR InParanoid; P87056; -.
DR OMA; IWNRESD; -.
DR PhylomeDB; P87056; -.
DR PRO; PR:P87056; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005811; C:lipid droplet; ISO:PomBase.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; ISO:PomBase.
DR GO; GO:0044255; P:cellular lipid metabolic process; IC:PomBase.
DR Gene3D; 3.40.50.1820; -; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR022742; Hydrolase_4.
DR Pfam; PF12146; Hydrolase_4; 1.
DR SUPFAM; SSF53474; SSF53474; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum; Glycoprotein; Hydrolase; Membrane;
KW Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix.
FT CHAIN 1..364
FT /note="Abhydrolase domain-containing protein C57A10.08c"
FT /id="PRO_0000312658"
FT TOPO_DOM 1..8
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 9..29
FT /note="Helical; Signal-anchor for type II membrane protein"
FT /evidence="ECO:0000255"
FT TOPO_DOM 30..364
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT ACT_SITE 183
FT /note="Charge relay system"
FT /evidence="ECO:0000250"
FT ACT_SITE 336
FT /note="Charge relay system"
FT /evidence="ECO:0000250"
FT CARBOHYD 326
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 364 AA; 41809 MW; 4219C777C87C28B9 CRC64;
MYFFTISRLT SFISYGILGA LGILTFLYLY DAYLAKSFQR LVIERRSKRE SLSKNLSPND
NSHNSKIDIS SDYQLLNEYK VAYYLRPGII PLNHNLAKQE VFVFLHGLGG QMSQFQKVMS
YFPPTACLFS FDYWGCGLSR QAFPNQRIGS VDQLTTKGLS KLTYKVLEKL FPENTQFILI
GHSMGATIAS RVSKMLQTRC TALLLLNPKI RFTSKEISMI VRLRKTPNAF ISLYRLLDRF
HGLRSSSVTR SLSKNIKGDG DAVRAQLWLW NRQSNTKIWK TMLMGLEELL EPGFHFPKCP
ILILFGEFDP VSSLKDKVFF QDYPGNYTFK EIDTGHCSML EQPSEVYNCI DSFLDKFSTT
DHNI
