YDJC_DANRE
ID YDJC_DANRE Reviewed; 313 AA.
AC A2BIR6;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 20-FEB-2007, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Carbohydrate deacetylase {ECO:0000250|UniProtKB:Q53WD3};
DE EC=3.5.1.- {ECO:0000250|UniProtKB:Q53WD3};
GN Name=ydjc; ORFNames=si:ch211-89f7.6;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
CC -!- FUNCTION: Probably catalyzes the deacetylation of acetylated
CC carbohydrates an important step in the degradation of oligosaccharides.
CC {ECO:0000250|UniProtKB:Q53WD3}.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000250|UniProtKB:Q53WD3};
CC -!- SIMILARITY: Belongs to the YdjC deacetylase family. {ECO:0000305}.
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DR EMBL; BX957246; CAM14368.1; -; Genomic_DNA.
DR RefSeq; NP_001076331.1; NM_001082862.1.
DR RefSeq; XP_005165107.1; XM_005165050.3.
DR RefSeq; XP_017211642.1; XM_017356153.1.
DR AlphaFoldDB; A2BIR6; -.
DR SMR; A2BIR6; -.
DR STRING; 7955.ENSDARP00000085284; -.
DR PaxDb; A2BIR6; -.
DR PRIDE; A2BIR6; -.
DR Ensembl; ENSDART00000090851; ENSDARP00000085284; ENSDARG00000062655.
DR Ensembl; ENSDART00000182189; ENSDARP00000153022; ENSDARG00000062655.
DR GeneID; 569036; -.
DR KEGG; dre:569036; -.
DR CTD; 150223; -.
DR ZFIN; ZDB-GENE-060526-182; ydjc.
DR eggNOG; ENOG502RYFJ; Eukaryota.
DR GeneTree; ENSGT00390000002575; -.
DR HOGENOM; CLU_064244_1_0_1; -.
DR InParanoid; A2BIR6; -.
DR OMA; HPQEGGC; -.
DR OrthoDB; 845079at2759; -.
DR PhylomeDB; A2BIR6; -.
DR TreeFam; TF329340; -.
DR PRO; PR:A2BIR6; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 5.
DR Bgee; ENSDARG00000062655; Expressed in blastula and 21 other tissues.
DR GO; GO:0019213; F:deacetylase activity; IBA:GO_Central.
DR GO; GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR006879; YdjC-like.
DR PANTHER; PTHR31609; PTHR31609; 1.
DR Pfam; PF04794; YdjC; 1.
DR SUPFAM; SSF88713; SSF88713; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism; Hydrolase; Magnesium; Metal-binding;
KW Reference proteome.
FT CHAIN 1..313
FT /note="Carbohydrate deacetylase"
FT /id="PRO_0000328776"
FT REGION 262..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 13
FT /note="Proton acceptor"
FT /evidence="ECO:0000250|UniProtKB:Q53WD3"
FT BINDING 14
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000250|UniProtKB:Q53WD3"
FT BINDING 133
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000250|UniProtKB:Q53WD3"
SQ SEQUENCE 313 AA; 34977 MW; E4CDAC8CC7FAF516 CRC64;
MPQPKVKLVV TGDDFGYCER RNQGIVDCFR AGGISNVSLL VNAVSAKHAA DLAKRYHMPI
GLHANLSEGL PVSQELKGST LLNKDGFFHG KMGFREVLHS GQLKMSEVEA ELRAQVNRFF
ELIGHMPYHM DGHQHVHVLP DVREVFAQVL SDFGITYTRV PIEPGLRFCN FLPSHLREFN
AQVEKDALES VEVFHRNGIR WPDVYLGLST MGKNMCLSNL KRALEASLDD GVSSPLILTQ
SNNAASNCYR PVTAELMVHP GYPSQPQQGG CGEGPDDFSQ STDRLHELNT LRDPMVLNFY
RQQGIHLCAF KDF
