YDJE_ECOLI
ID YDJE_ECOLI Reviewed; 452 AA.
AC P38055; P77244;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 2.
DT 03-AUG-2022, entry version 148.
DE RecName: Full=Inner membrane metabolite transport protein YdjE;
GN Name=ydjE; OrderedLocusNames=b1769, JW1758;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA Wada C., Yamamoto Y., Horiuchi T.;
RT "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 28.0-40.1 min region on the linkage map.";
RL DNA Res. 3:363-377(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 360-452.
RC STRAIN=K12;
RX PubMed=2670682; DOI=10.1016/0378-1119(89)90312-0;
RA Jerlstroem P.G., Bezjak D.A., Jennings M.P., Beacham I.R.;
RT "Structure and expression in Escherichia coli K-12 of the L-asparaginase I-
RT encoding ansA gene and its flanking regions.";
RL Gene 78:37-46(1989).
RN [5]
RP IDENTIFICATION.
RX PubMed=7984428; DOI=10.1093/nar/22.22.4756;
RA Borodovsky M., Rudd K.E., Koonin E.V.;
RT "Intrinsic and extrinsic approaches for detecting genes in a bacterial
RT genome.";
RL Nucleic Acids Res. 22:4756-4767(1994).
RN [6]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000305}.
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DR EMBL; U00096; AAC74839.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA15560.1; -; Genomic_DNA.
DR EMBL; M26934; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; A64937; A64937.
DR RefSeq; NP_416283.1; NC_000913.3.
DR RefSeq; WP_000438807.1; NZ_SSZK01000001.1.
DR AlphaFoldDB; P38055; -.
DR SMR; P38055; -.
DR BioGRID; 4259142; 243.
DR STRING; 511145.b1769; -.
DR TCDB; 2.A.1.1.92; the major facilitator superfamily (mfs).
DR PaxDb; P38055; -.
DR PRIDE; P38055; -.
DR EnsemblBacteria; AAC74839; AAC74839; b1769.
DR EnsemblBacteria; BAA15560; BAA15560; BAA15560.
DR GeneID; 946274; -.
DR KEGG; ecj:JW1758; -.
DR KEGG; eco:b1769; -.
DR PATRIC; fig|1411691.4.peg.485; -.
DR EchoBASE; EB2272; -.
DR eggNOG; COG2814; Bacteria.
DR HOGENOM; CLU_001265_46_6_6; -.
DR InParanoid; P38055; -.
DR OMA; MSWWLVP; -.
DR PhylomeDB; P38055; -.
DR BioCyc; EcoCyc:YDJE-MON; -.
DR PRO; PR:P38055; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR Pfam; PF00083; Sugar_tr; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..452
FT /note="Inner membrane metabolite transport protein YdjE"
FT /id="PRO_0000050484"
FT TOPO_DOM 1..20
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 21..43
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 44..57
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 58..80
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 81..91
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 92..114
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 115..117
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 118..140
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 141..152
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 153..175
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 176..178
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 179..198
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 199..265
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 266..288
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 289..297
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 298..320
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TOPO_DOM 321..326
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 327..344
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TOPO_DOM 345..353
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 354..376
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TOPO_DOM 377..388
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 389..411
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT TOPO_DOM 412..415
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 416..438
FT /note="Helical; Name=12"
FT /evidence="ECO:0000255"
FT TOPO_DOM 439..452
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 452 AA; 50318 MW; 5A596DEA229205C2 CRC64;
MEQYDQIGAR LDRLPLARFH YRIFGIISFS LLLTGFLSYS GNVVLAKLVS NGWSNNFLNA
AFTSALMFGY FIGSLTGGFI GDYFGRRRAF RINLLIVGIA ATGAAFVPDM YWLIFFRFLM
GTGMGALIMV GYASFTEFIP ATVRGKWSAR LSFVGNWSPM LSAAIGVVVI AFFSWRIMFL
LGGIGILLAW FLSGKYFIES PRWLAGKGQI AGAECQLREV EQQIEREKSI RLPPLTSYQS
NSKVKVIKGT FWLLFKGEML RRTLVAITVL IAMNISLYTI TVWIPTIFVN SGIDVDKSIL
MTAVIMIGAP VGIFIAALII DHFPRRLFGS TLLIIIAVLG YIYSIQTTEW AILIYGLVMI
FFLYMYVCFA SAVYIPELWP THLRLRGSGF VNAVGRIVAV FTPYGVAALL THYGSITVFM
VLGVMLLLCA LVLSIFGIET RKVSLEEISE VN
