YDJM_ECOLI
ID YDJM_ECOLI Reviewed; 196 AA.
AC P64481; P76209; Q2MB45;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 24-NOV-2009, sequence version 2.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Inner membrane protein YdjM;
GN Name=ydjM; OrderedLocusNames=b1728, JW5281;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [3]
RP REGULATION BY LEXA, AND INDUCTION.
RC STRAIN=K12 / RW118;
RX PubMed=10760155; DOI=10.1046/j.1365-2958.2000.01826.x;
RA Fernandez De Henestrosa A.R., Ogi T., Aoyagi S., Chafin D., Hayes J.J.,
RA Ohmori H., Woodgate R.;
RT "Identification of additional genes belonging to the LexA regulon in
RT Escherichia coli.";
RL Mol. Microbiol. 35:1560-1572(2000).
RN [4]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein
CC {ECO:0000305|PubMed:15919996}.
CC -!- INDUCTION: Repressed by LexA, induced by DNA damage; it has 2 LexA
CC binding sites both of which bind LexA with high affinity in a
CC cooperative manner. {ECO:0000269|PubMed:10760155}.
CC -!- SIMILARITY: To B.subtilis YvsG. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U00096; AAC74798.4; -; Genomic_DNA.
DR EMBL; AP009048; BAE76511.1; -; Genomic_DNA.
DR PIR; H64931; H64931.
DR RefSeq; NP_416242.6; NC_000913.3.
DR RefSeq; WP_001297653.1; NZ_STEB01000009.1.
DR AlphaFoldDB; P64481; -.
DR BioGRID; 4261487; 66.
DR STRING; 511145.b1728; -.
DR PaxDb; P64481; -.
DR PRIDE; P64481; -.
DR EnsemblBacteria; AAC74798; AAC74798; b1728.
DR EnsemblBacteria; BAE76511; BAE76511; BAE76511.
DR GeneID; 66674378; -.
DR GeneID; 945644; -.
DR KEGG; ecj:JW5281; -.
DR KEGG; eco:b1728; -.
DR PATRIC; fig|1411691.4.peg.528; -.
DR EchoBASE; EB3745; -.
DR eggNOG; COG1988; Bacteria.
DR HOGENOM; CLU_097802_2_1_6; -.
DR InParanoid; P64481; -.
DR OMA; GHRGMTH; -.
DR PhylomeDB; P64481; -.
DR BioCyc; EcoCyc:G6933-MON; -.
DR PRO; PR:P64481; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0006974; P:cellular response to DNA damage stimulus; IEP:EcoliWiki.
DR InterPro; IPR016956; YdjM.
DR InterPro; IPR007404; YdjM-like.
DR Pfam; PF04307; YdjM; 1.
DR PIRSF; PIRSF030780; Md_memb_hyd_prd; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..196
FT /note="Inner membrane protein YdjM"
FT /id="PRO_0000013857"
FT TOPO_DOM 1..23
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 24..44
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 45..77
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 78..98
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 99..106
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 107..127
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 128..149
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 150..170
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 171..196
FT /note="Periplasmic"
FT /evidence="ECO:0000269|PubMed:15919996"
SQ SEQUENCE 196 AA; 22350 MW; 9CB6F59FAD010235 CRC64;
MTAEGHLLFS IACAVFAKNA ELTPVLAQGD WWHIVPSAIL TCLLPDIDHP KSFLGQRLKW
ISKPIARAFG HRGFTHSLLA VFALLATFYL KVPEGWFIPA DALQGMVLGY LSHILADMLT
PAGVPLLWPC RWRFRLPILV PQKGNQLERF ICMALFVWSV WMPHSLPENS AVRWSSQMIN
TLQIQFHRLI KHQVEY
