YDSB_SCHPO
ID YDSB_SCHPO Reviewed; 846 AA.
AC O14186;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 130.
DE RecName: Full=Uncharacterized WD repeat-containing protein C4F8.11;
GN ORFNames=SPAC4F8.11;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
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DR EMBL; CU329670; CAB11058.1; -; Genomic_DNA.
DR PIR; T38840; T38840.
DR RefSeq; NP_593862.1; NM_001019291.2.
DR AlphaFoldDB; O14186; -.
DR SMR; O14186; -.
DR BioGRID; 279936; 5.
DR STRING; 4896.SPAC4F8.11.1; -.
DR iPTMnet; O14186; -.
DR MaxQB; O14186; -.
DR PaxDb; O14186; -.
DR PRIDE; O14186; -.
DR EnsemblFungi; SPAC4F8.11.1; SPAC4F8.11.1:pep; SPAC4F8.11.
DR GeneID; 2543518; -.
DR KEGG; spo:SPAC4F8.11; -.
DR PomBase; SPAC4F8.11; -.
DR VEuPathDB; FungiDB:SPAC4F8.11; -.
DR eggNOG; KOG0269; Eukaryota.
DR HOGENOM; CLU_341047_0_0_1; -.
DR InParanoid; O14186; -.
DR OMA; SCNDVKW; -.
DR PhylomeDB; O14186; -.
DR PRO; PR:O14186; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0061700; C:GATOR2 complex; IPI:PomBase.
DR GO; GO:0005774; C:vacuolar membrane; EXP:PomBase.
DR GO; GO:0034198; P:cellular response to amino acid starvation; IBA:GO_Central.
DR GO; GO:0016239; P:positive regulation of macroautophagy; IBA:GO_Central.
DR GO; GO:1904263; P:positive regulation of TORC1 signaling; ISO:PomBase.
DR GO; GO:0070647; P:protein modification by small protein conjugation or removal; IC:PomBase.
DR Gene3D; 2.130.10.10; -; 2.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR037590; WDR24.
DR PANTHER; PTHR46200; PTHR46200; 1.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome; Repeat; WD repeat.
FT CHAIN 1..846
FT /note="Uncharacterized WD repeat-containing protein
FT C4F8.11"
FT /id="PRO_0000051494"
FT REPEAT 88..129
FT /note="WD 1"
FT REPEAT 132..172
FT /note="WD 2"
FT REPEAT 175..215
FT /note="WD 3"
FT REPEAT 219..258
FT /note="WD 4"
FT REPEAT 262..309
FT /note="WD 5"
FT REPEAT 313..348
FT /note="WD 6"
FT REPEAT 624..663
FT /note="WD 7"
FT REGION 541..560
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 846 AA; 93228 MW; 7B76FD17B59BC0F5 CRC64;
MPSRNSNVLQ RPTYAQLAST SVKSSKGLVS YQDWVVDVKA SISAISVNKS RTKVGVAGRE
LLKVLAVNPN SSKPPVCISD LLQKSTQTKH ISCNDVKWGS SFASNLIFTC SPLGNLNVWD
VNLEALLYDF NEHSRAVHKL DISSFHPSYV LTASQDGLIK LWDYKESSST ITFRGNSEAA
RDVVFSPSEP NEFVAAYDSG ILQKWDIRFP KLPFLKLAAH NGVVLCVNYS PNGVFLASCG
RDKTIRIWDS TSNKKKSLIT INNVSPLNCV RWRPANQQSR GSNQLASSSL VGDTAINVWD
ITRPYIPYRT VSCHDSIVST MHWASTELLW SCSKDGIFSQ TRVENAFNCI DMLPRATSSW
STKNSLVFSS NPISNQRLSS LNRVASFESN ISSLKSALYA SQNSDGSTSN PVPFVPHNFV
GIPQELGILA YRSEDVAQFC YLAKNYRISG DISSACKENA FFARNVGAEF AYQIWDALYF
SLGVLNNSDK GISELINIPF VSANNSMADD EKGRNLKNLT QISTSSTPAH DNLSLNDFFE
PREASTPSES SNSSIESEDN LDKAVLNKQS QWHDLENPIV LKKGQAPVNN FSTDSRASIN
SSYLLDSAAS NYSGTSHNEM FNSFHRSSVT SASIKSREAV LSAGNSSRRA SIFLDQLSLH
GDTDSEIPID DLPPIELPYV VTSIISDCIS RGDVQTAACV CSVFSYLTID LPRIQLDDLL
ESYVDLLRRF GMFSEATLLI NMSGSKNLKY IHSSSRDLIF EMENKKATGN EQSEKGKENA
KTVTSLKKCV YCELPLRGVL VYPPVCGHIG HESCLRSWYF DNTDDALPVC PVPGCGVKLL
DKRALI