ID   YDYB_SCHPO              Reviewed;         942 AA.
AC   O13690;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=PH and SEC7 domain-containing protein C11E3.11c;
GN   ORFNames=SPAC11E3.11c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
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DR   EMBL; CU329670; CAB11190.1; -; Genomic_DNA.
DR   PIR; T37539; T37539.
DR   RefSeq; NP_594936.1; NM_001020367.2.
DR   AlphaFoldDB; O13690; -.
DR   SMR; O13690; -.
DR   BioGRID; 278276; 4.
DR   STRING; 4896.SPAC11E3.11c.1; -.
DR   iPTMnet; O13690; -.
DR   SwissPalm; O13690; -.
DR   MaxQB; O13690; -.
DR   PaxDb; O13690; -.
DR   PRIDE; O13690; -.
DR   EnsemblFungi; SPAC11E3.11c.1; SPAC11E3.11c.1:pep; SPAC11E3.11c.
DR   GeneID; 2541783; -.
DR   KEGG; spo:SPAC11E3.11c; -.
DR   PomBase; SPAC11E3.11c; -.
DR   VEuPathDB; FungiDB:SPAC11E3.11c; -.
DR   eggNOG; KOG0929; Eukaryota.
DR   HOGENOM; CLU_323935_0_0_1; -.
DR   InParanoid; O13690; -.
DR   OMA; CHIVLFS; -.
DR   PhylomeDB; O13690; -.
DR   Reactome; R-SPO-199992; trans-Golgi Network Vesicle Budding.
DR   Reactome; R-SPO-5620916; VxPx cargo-targeting to cilium.
DR   Reactome; R-SPO-6807878; COPI-mediated anterograde transport.
DR   Reactome; R-SPO-6811434; COPI-dependent Golgi-to-ER retrograde traffic.
DR   Reactome; R-SPO-6811438; Intra-Golgi traffic.
DR   PRO; PR:O13690; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005938; C:cell cortex; IDA:PomBase.
DR   GO; GO:0051285; C:cell cortex of cell tip; IDA:PomBase.
DR   GO; GO:0032153; C:cell division site; IDA:PomBase.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; ISM:PomBase.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:PomBase.
DR   GO; GO:0051523; P:cell growth mode switching, monopolar to bipolar; IMP:PomBase.
DR   GO; GO:0006886; P:intracellular protein transport; ISM:PomBase.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   GO; GO:0023052; P:signaling; IC:PomBase.
DR   GO; GO:0016192; P:vesicle-mediated transport; ISM:PomBase.
DR   CDD; cd00171; Sec7; 1.
DR   Gene3D; 1.10.1000.11; -; 1.
DR   Gene3D; 2.30.29.30; -; 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR041681; PH_9.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR023394; Sec7_C_sf.
DR   InterPro; IPR000904; Sec7_dom.
DR   InterPro; IPR035999; Sec7_dom_sf.
DR   Pfam; PF15410; PH_9; 1.
DR   Pfam; PF01369; Sec7; 1.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00222; Sec7; 1.
DR   SUPFAM; SSF48425; SSF48425; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50190; SEC7; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..942
FT                   /note="PH and SEC7 domain-containing protein C11E3.11c"
FT                   /id="PRO_0000317153"
FT   DOMAIN          295..497
FT                   /note="SEC7"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00189"
FT   DOMAIN          681..804
FT                   /note="PH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00145"
FT   REGION          1..128
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          259..308
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..74
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        88..125
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        288..308
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   942 AA;  105909 MW;  A677CE2E619ECDF4 CRC64;
     MSRNASNAYL KNGNSTPSND KRSPSSLSQR SKTSTRSSKP FLQRLFPSTW FKNESSSRHP
     LTSIKENDTQ TIGRRPSMRV KLFGKDKSKA SMSTNDLPSH PRSQSVMGFS SSTSQLTGTS
     NSSRTRLNKD MRRDFGMTSM SSITSSTPTP SQLPVRPSTS LSFFDDIPLG PSFSAETILS
     SLSISTSNNA MSKTTPAPPL VTTKSISADQ DDFYTCKEEV STYEGLNSQI ELSPVKSRDS
     QNKSAKNLST AYRTVSGESR NLMVDPKVSP YGNSRTPLRD SSNYLRDRRS INRQSSLSIP
     KSTSETTRKT LALSNGGIDQ SRVSSDSFKV DDSSAKMAAI DIWEGSQHIV SNDKALSWLV
     TDKPYNKAVL KHYISLYDFE NTDILQSLRM ICGNLYVHGE TQELDHFLGE FSNQWCRTNP
     KGLFCNPQIV HSIAFSLLLL NTDLHIAELS ASERMSRNQF VENTYRSIKQ ALNDSFDGNE
     EKKNAFFLSS YKSFASNESC NSPAIHSLHG NLSPGKSAEL KKLHKRSLSS KVLEEAFSSY
     WMSALKEMYH SIKVSMILQP DRYLDMNFDF NDTNKINNPS STANQTRHFH SVSEIKKLPM
     GTDELEKSMV RPSTAMYINR QNENAVSIDK SRDLQGTVNT KEIRSRSALS YQNDRPLATD
     LPSVIYNHKH PNVVSPFYVH PYIKQGILKF QSKESHKFRK KEVWSTVLAV LQRDVFTLYN
     LNTPNLSYDP KDLDISKVGK PVIKTTIIAS LAKPFPSSED AVVLKSTNSL YFDLETSSQL
     KLRFAGPSPK DAQGWIDALN YWAARSSKVP LLGGVTNVDY GWARCTGQRA QKSNAQLLKT
     KTDKIIVHKW QPQPVNTIPS SLSLGEQLSA FNNFMKLLKK TNDEHQNLHK EMLVVLSSQP
     KSTFRRAVEN WKYKSDYLQL NLVRLRVYIS VLEKYKSQAQ NS