ID   YDZA_SCHPO              Reviewed;         329 AA.
AC   O13717;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 113.
DE   RecName: Full=Uncharacterized protein C14C4.10c;
GN   ORFNames=SPAC14C4.10c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; CU329670; CAB11203.1; -; Genomic_DNA.
DR   PIR; T37695; T37695.
DR   RefSeq; NP_594915.1; NM_001020347.2.
DR   AlphaFoldDB; O13717; -.
DR   BioGRID; 277927; 3.
DR   STRING; 4896.SPAC14C4.10c.1; -.
DR   SwissPalm; O13717; -.
DR   MaxQB; O13717; -.
DR   PaxDb; O13717; -.
DR   EnsemblFungi; SPAC14C4.10c.1; SPAC14C4.10c.1:pep; SPAC14C4.10c.
DR   GeneID; 2541421; -.
DR   KEGG; spo:SPAC14C4.10c; -.
DR   PomBase; SPAC14C4.10c; -.
DR   VEuPathDB; FungiDB:SPAC14C4.10c; -.
DR   eggNOG; KOG3069; Eukaryota.
DR   HOGENOM; CLU_845090_0_0_1; -.
DR   InParanoid; O13717; -.
DR   OMA; LLWGITH; -.
DR   PhylomeDB; O13717; -.
DR   Reactome; R-SPO-9033241; Peroxisomal protein import.
DR   PRO; PR:O13717; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR   GO; GO:0005794; C:Golgi apparatus; HDA:PomBase.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003986; F:acetyl-CoA hydrolase activity; IBA:GO_Central.
DR   GO; GO:0010945; F:CoA pyrophosphatase activity; IEA:InterPro.
DR   GO; GO:0015938; P:coenzyme A catabolic process; IBA:GO_Central.
DR   CDD; cd03426; CoAse; 1.
DR   InterPro; IPR045121; CoAse.
DR   InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR   InterPro; IPR000086; NUDIX_hydrolase_dom.
DR   PANTHER; PTHR12992; PTHR12992; 1.
DR   Pfam; PF00293; NUDIX; 1.
DR   SUPFAM; SSF55811; SSF55811; 1.
DR   PROSITE; PS51462; NUDIX; 1.
PE   4: Predicted;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..329
FT                   /note="Uncharacterized protein C14C4.10c"
FT                   /id="PRO_0000116685"
FT   TRANSMEM        123..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        303..323
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          27..185
FT                   /note="Nudix hydrolase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00794"
SQ   SEQUENCE   329 AA;  38294 MW;  5DB9C067BA1E1743 CRC64;
     MELELDLLTG LQLLSEYCPR VTPNAPPRRA SVAVIIAFKE SQDFSNPKWP QCIPITSVPY
     VLLIQRSFRD TDRWSGHMAL PGGTRSLTDK SDIQTAHRET LEEVGIDLRK EHAHFVGALD
     ERVITSNWGQ FPLLLLSSFV FILPYMPSLR LQESEVFSAQ WYPLADLLLP ECQTRIQIDS
     SRALKKTYPR FIKTLFHLAV GNLMYSAIRL EFDPSSATYS LPPYQRPFLR GITHSIFVDL
     FIFLSPSSAR HCLCWSLPYF QHYDLRFIAS FFTQFYRLRL HQVYPRGNWV FTCLNGYYPY
     LKLTLLVGFL FRLFLVYLLF LIISAYYKS