ID   YE11_YEAST              Reviewed;         107 AA.
AC   P40097; A0A1S0T074;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Uncharacterized protein YER181C, mitochondrial;
GN   OrderedLocusNames=YER181C;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169868;
RA   Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E.,
RA   Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E.,
RA   Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S.,
RA   Hyman R.W., Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D.,
RA   Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X.,
RA   Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y.,
RA   Botstein D., Davis R.W.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome V.";
RL   Nature 387:78-81(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 76625 / YPH499;
RX   PubMed=14576278; DOI=10.1073/pnas.2135385100;
RA   Sickmann A., Reinders J., Wagner Y., Joppich C., Zahedi R.P., Meyer H.E.,
RA   Schoenfisch B., Perschil I., Chacinska A., Guiard B., Rehling P.,
RA   Pfanner N., Meisinger C.;
RT   "The proteome of Saccharomyces cerevisiae mitochondria.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:13207-13212(2003).
RN   [4]
RP   INDUCTION.
RX   PubMed=16764994; DOI=10.1016/j.bbagen.2006.02.014;
RA   Jablonka W., Guzman S., Ramirez J., Montero-Lomeli M.;
RT   "Deviation of carbohydrate metabolism by the SIT4 phosphatase in
RT   Saccharomyces cerevisiae.";
RL   Biochim. Biophys. Acta 1760:1281-1291(2006).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane
CC       {ECO:0000269|PubMed:14576278}; Multi-pass membrane protein
CC       {ECO:0000269|PubMed:14576278}.
CC   -!- INDUCTION: Down-regulated in the absence of SIT4.
CC       {ECO:0000269|PubMed:16764994}.
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DR   EMBL; U18922; AAB64708.1; -; Genomic_DNA.
DR   EMBL; BK006939; DAA80290.1; -; Genomic_DNA.
DR   PIR; S50684; S50684.
DR   AlphaFoldDB; P40097; -.
DR   DIP; DIP-5471N; -.
DR   PaxDb; P40097; -.
DR   EnsemblFungi; YER181C_mRNA; YER181C; YER181C.
DR   SGD; S000000983; YER181C.
DR   HOGENOM; CLU_2212008_0_0_1; -.
DR   PRO; PR:P40097; -.
DR   Proteomes; UP000002311; Chromosome V.
DR   RNAct; P40097; protein.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; HDA:SGD.
PE   2: Evidence at transcript level;
KW   Membrane; Mitochondrion; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..107
FT                   /note="Uncharacterized protein YER181C, mitochondrial"
FT                   /id="PRO_0000202659"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        58..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   107 AA;  12458 MW;  56B49B368BED47B3 CRC64;
     MLILLRLSEV CVNFVIIIGI PLLIEASILC IQNILELLLK GIGILKFNRY LHTIILRLFF
     LSFYMLHFPI TLSILAFQLP LNLLTLSQAS FHLPRSHMIL YQQQECY