ID   YE29_HELPJ              Reviewed;         329 AA.
AC   Q9ZJI5;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Uncharacterized protein jhp_1324;
GN   OrderedLocusNames=jhp_1324;
OS   Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=J99 / ATCC 700824;
RX   PubMed=9923682; DOI=10.1038/16495;
RA   Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C.,
RA   Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G., Tummino P.J.,
RA   Caruso A., Uria-Nickelsen M., Mills D.M., Ives C., Gibson R., Merberg D.,
RA   Mills S.D., Jiang Q., Taylor D.E., Vovis G.F., Trust T.J.;
RT   "Genomic sequence comparison of two unrelated isolates of the human gastric
RT   pathogen Helicobacter pylori.";
RL   Nature 397:176-180(1999).
CC   -!- SIMILARITY: Belongs to the SIS family. GutQ/KpsF subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AE001439; AAD06900.1; -; Genomic_DNA.
DR   PIR; G71821; G71821.
DR   RefSeq; WP_001121965.1; NZ_CP011330.1.
DR   AlphaFoldDB; Q9ZJI5; -.
DR   SMR; Q9ZJI5; -.
DR   STRING; 85963.jhp_1324; -.
DR   EnsemblBacteria; AAD06900; AAD06900; jhp_1324.
DR   KEGG; hpj:jhp_1324; -.
DR   PATRIC; fig|85963.30.peg.1236; -.
DR   eggNOG; COG0517; Bacteria.
DR   eggNOG; COG0794; Bacteria.
DR   OMA; LMACLMR; -.
DR   Proteomes; UP000000804; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016853; F:isomerase activity; IEA:InterPro.
DR   GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd05014; SIS_Kpsf; 1.
DR   Gene3D; 3.10.580.10; -; 1.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR004800; KdsD/KpsF-type.
DR   InterPro; IPR001347; SIS_dom.
DR   InterPro; IPR046348; SIS_dom_sf.
DR   InterPro; IPR035474; SIS_Kpsf.
DR   Pfam; PF00571; CBS; 2.
DR   Pfam; PF01380; SIS; 1.
DR   PIRSF; PIRSF004692; KdsD_KpsF; 1.
DR   SMART; SM00116; CBS; 1.
DR   SUPFAM; SSF53697; SSF53697; 1.
DR   TIGRFAMs; TIGR00393; kpsF; 1.
DR   PROSITE; PS51371; CBS; 2.
DR   PROSITE; PS51464; SIS; 1.
PE   3: Inferred from homology;
KW   ATP-binding; CBS domain; Nucleotide-binding; Repeat.
FT   CHAIN           1..329
FT                   /note="Uncharacterized protein jhp_1324"
FT                   /id="PRO_0000136588"
FT   DOMAIN          38..184
FT                   /note="SIS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00797"
FT   DOMAIN          211..267
FT                   /note="CBS 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   DOMAIN          276..329
FT                   /note="CBS 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   BINDING         56..61
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   329 AA;  35948 MW;  A63E3DAFE733BAC1 CRC64;
     MPILFDCNAT AIQVLRDEAS ALLESVKQFQ EPNDLEAIVK LILKSQEKGG KLVIVGVGKS
     ALVAQKIVAS MLSTGNRSAF LHPTEAMHGD LGMVEKNDVI LMISYGGESL ELLNLVSHLK
     RLSHKIITFT KSPTSSLSKL GDYYLSLKIK KEACPINTAP TTSTTLTLAL GDVLMACLMR
     AKNFSQEDFA SFHPGGLLGK KLFVKVKDLL QTTNLPLIAP STSFKDALIE MSEKRLGSAI
     LVNDNNELVG VLSDGDVRRA LLKGLSLESE VKHFATLKPK SFKNLDALLL EALEFLERHK
     IQLLVCVDDR NKVLGVLHLH QLLELGLKA