ID   YE2H4_CAEEL             Reviewed;         518 AA.
AC   Q19040;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2010, sequence version 3.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Uncharacterized protein E02H4.4;
DE   Flags: Precursor;
GN   ORFNames=E02H4.4;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [2]
RP   GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-295, AND IDENTIFICATION BY MASS
RP   SPECTROMETRY.
RC   STRAIN=Bristol N2;
RX   PubMed=12754521; DOI=10.1038/nbt829;
RA   Kaji H., Saito H., Yamauchi Y., Shinkawa T., Taoka M., Hirabayashi J.,
RA   Kasai K., Takahashi N., Isobe T.;
RT   "Lectin affinity capture, isotope-coded tagging and mass spectrometry to
RT   identify N-linked glycoproteins.";
RL   Nat. Biotechnol. 21:667-672(2003).
RN   [3]
RP   GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-295 AND ASN-362, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RC   STRAIN=Bristol N2;
RX   PubMed=17761667; DOI=10.1074/mcp.m600392-mcp200;
RA   Kaji H., Kamiie J., Kawakami H., Kido K., Yamauchi Y., Shinkawa T.,
RA   Taoka M., Takahashi N., Isobe T.;
RT   "Proteomics reveals N-linked glycoprotein diversity in Caenorhabditis
RT   elegans and suggests an atypical translocation mechanism for integral
RT   membrane proteins.";
RL   Mol. Cell. Proteomics 6:2100-2109(2007).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
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DR   EMBL; Z68003; CAA91977.3; -; Genomic_DNA.
DR   PIR; T20422; T20422.
DR   RefSeq; NP_510379.3; NM_077978.3.
DR   AlphaFoldDB; Q19040; -.
DR   iPTMnet; Q19040; -.
DR   EPD; Q19040; -.
DR   PaxDb; Q19040; -.
DR   EnsemblMetazoa; E02H4.4.1; E02H4.4.1; WBGene00008462.
DR   GeneID; 183995; -.
DR   KEGG; cel:CELE_E02H4.4; -.
DR   UCSC; E02H4.4; c. elegans.
DR   CTD; 183995; -.
DR   WormBase; E02H4.4; CE44096; WBGene00008462; -.
DR   eggNOG; ENOG502TG1S; Eukaryota.
DR   GeneTree; ENSGT00550000075913; -.
DR   HOGENOM; CLU_520963_0_0_1; -.
DR   InParanoid; Q19040; -.
DR   OMA; LNFYDAS; -.
DR   OrthoDB; 1768695at2759; -.
DR   PRO; PR:Q19040; -.
DR   Proteomes; UP000001940; Chromosome X.
DR   Bgee; WBGene00008462; Expressed in embryo and 3 other tissues.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.120.290; -; 1.
DR   InterPro; IPR035914; Sperma_CUB_dom_sf.
DR   SUPFAM; SSF49854; SSF49854; 1.
PE   1: Evidence at protein level;
KW   Glycoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..518
FT                   /note="Uncharacterized protein E02H4.4"
FT                   /id="PRO_0000250572"
FT   DOMAIN          389..517
FT                   /note="CUB"
FT   CARBOHYD        30
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        142
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        295
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000269|PubMed:12754521,
FT                   ECO:0000269|PubMed:17761667"
FT   CARBOHYD        342
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        362
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000269|PubMed:17761667"
FT   CARBOHYD        410
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        503
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   518 AA;  56155 MW;  33CD47208583D6FC CRC64;
     MWKWKVILLF LAEMFVSGVN GDCACYEANN VTGKSAPISN SYMTEDFSPC YLPCSYVAYS
     GDETYGWTGL VLNWKTTTNS GGIIQIFDGP SATGTPIIQV AEGETIAAGI GKSLIKSSLP
     VITIKYSQTG SGASMFILNI NNGTFVTNVY YGSISTAAGL APIAVSTTTT AMPTTRSYSN
     PNFAYDPYFI THDIFVVINQ RTSGGMAALT SLNALAINFV TLLSTTTDIN SVSSSRLSLA
     TLTPYDPYYS VQGGIWELSA TDVLNNVPRS GVTIEGDIDS ALIGLADLAF TVNKNASTDT
     RNNVQRSVVL LTAEWPSNAL LGDNVASKFT ELGLNLLVVG YNLTDAETSQ LLRTDRWYNA
     INSSDSKITN VAAFVNPFYF NNGANNFWCP PFGITNSVDG TYSWFQEPYN YTGPHGINGV
     WTDPFDGQTG RYCNFANNQY VYQNNAGGSV KVQVYFELEA GKDFLNFYDA SNNLIASFTG
     YEIAGSSFFT STTTLTARFT SDNKSIFRGF WVSITPQP