YEAV_ECOLI
ID YEAV_ECOLI Reviewed; 481 AA.
AC P0ABD1; P76252; P97208;
DT 08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 08-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Uncharacterized transporter YeaV;
GN Name=yeaV; OrderedLocusNames=b1801, JW5293;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097040; DOI=10.1093/dnares/3.6.379;
RA Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K.,
RA Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T.,
RA Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S., Nakamura Y.,
RA Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y.,
RA Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y.,
RA Horiuchi T.;
RT "A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 40.1-50.0 min region on the linkage map.";
RL DNA Res. 3:379-392(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP DISRUPTION PHENOTYPE.
RC STRAIN=K12 / MC4100 / ATCC 35695 / DSM 6574;
RX PubMed=20233924; DOI=10.1128/jb.01665-09;
RA Lukas H., Reimann J., Kim O.B., Grimpo J., Unden G.;
RT "Regulation of aerobic and anaerobic D-malate metabolism of Escherichia
RT coli by the LysR-type regulator DmlR (YeaT).";
RL J. Bacteriol. 192:2503-2511(2010).
CC -!- FUNCTION: Probable transporter whose substrate is unknown. Is not
CC involved in aerobic D-malate transport.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- DISRUPTION PHENOTYPE: Deletion of yeaV has no effect on the aerobic
CC growth with D-malate as the sole carbon source.
CC {ECO:0000269|PubMed:20233924}.
CC -!- SIMILARITY: Belongs to the BCCT transporter (TC 2.A.15) family.
CC {ECO:0000305}.
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DR EMBL; U00096; AAC74871.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA15596.2; -; Genomic_DNA.
DR PIR; A64941; A64941.
DR RefSeq; NP_416315.1; NC_000913.3.
DR RefSeq; WP_001301380.1; NZ_CP011343.2.
DR AlphaFoldDB; P0ABD1; -.
DR SMR; P0ABD1; -.
DR BioGRID; 4260336; 198.
DR STRING; 511145.b1801; -.
DR PaxDb; P0ABD1; -.
DR PRIDE; P0ABD1; -.
DR EnsemblBacteria; AAC74871; AAC74871; b1801.
DR EnsemblBacteria; BAA15596; BAA15596; BAA15596.
DR GeneID; 947326; -.
DR KEGG; ecj:JW5293; -.
DR KEGG; eco:b1801; -.
DR PATRIC; fig|511145.12.peg.1877; -.
DR EchoBASE; EB3281; -.
DR eggNOG; COG1292; Bacteria.
DR HOGENOM; CLU_010118_6_0_6; -.
DR InParanoid; P0ABD1; -.
DR OMA; VWFAWAP; -.
DR PhylomeDB; P0ABD1; -.
DR BioCyc; EcoCyc:YEAV-MON; -.
DR PRO; PR:P0ABD1; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0071705; P:nitrogen compound transport; IEA:InterPro.
DR InterPro; IPR018093; BCCT_CS.
DR InterPro; IPR000060; BCCT_transptr.
DR PANTHER; PTHR30047; PTHR30047; 1.
DR Pfam; PF02028; BCCT; 1.
DR TIGRFAMs; TIGR00842; bcct; 1.
DR PROSITE; PS01303; BCCT; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..481
FT /note="Uncharacterized transporter YeaV"
FT /id="PRO_0000201494"
FT TRANSMEM 32..52
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 82..102
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 137..157
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 173..193
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 204..224
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 258..278
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 289..309
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 348..368
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 392..412
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 418..438
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 481 AA; 52881 MW; 4F0DC3EB613F737A CRC64;
MVLLAMGLVI YLATSKYGNI RLGEGKPEYS TLSWLFMFIC AGLGSSTLYW GVAEWAYYYQ
TPGLNIAPRS QQALEFSVPY SFFHWGISAW ATYTLASLIM AYHFHVRKNK GLSLSGIIAA
ITGVRPQGPW GKLVDLMFLI ATVGALTISL VVTAATFTRG LSALTGLPDN FTVQAFVILL
SGGIFCLSSW IGINNGLQRL SKMVGWGAFL LPLLVLIVGP TEFITNSIIN AIGLTTQNFL
QMSLFTDPLG DGSFTRNWTV FYWLWWISYT PGVAMFVTRV SRGRKIKEVI WGLILGSTVG
CWFFFGVMES YAIHQFINGV INVPQVLETL GGETAVQQVL MSLPAGKLFL AAYLGVMIIF
LASHMDAVAY TMAATSTRNL QEGDDPDRGL RLFWCVVITL IPLSILFTGA SLETMKTTVV
LTALPFLVIL LVKVGGFIRW LKQDYADIPA HQVEHYLPQT PVEALEKTPV LPAGTVFKGD
N
