YEBS_ECOLI
ID YEBS_ECOLI Reviewed; 427 AA.
AC P0AD03; O07977; O07979; P76271;
DT 22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 22-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=Intermembrane transport protein YebS {ECO:0000305};
GN Name=yebS; OrderedLocusNames=b1833, JW1822;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097040; DOI=10.1093/dnares/3.6.379;
RA Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K.,
RA Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T.,
RA Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S., Nakamura Y.,
RA Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y.,
RA Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y.,
RA Horiuchi T.;
RT "A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 40.1-50.0 min region on the linkage map.";
RL DNA Res. 3:379-392(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP TOPOLOGY [LARGE SCALE ANALYSIS], AND SUBCELLULAR LOCATION.
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
RN [5]
RP FUNCTION, SUBUNIT, SUBCELLULAR LOCATION, TOPOLOGY, AND INDUCTION.
RX PubMed=27795327; DOI=10.1128/jb.00606-16;
RA Nakayama T., Zhang-Akiyama Q.M.;
RT "pqiABC and yebST, putative mce operons of Escherichia coli, encode
RT transport pathways and contribute to membrane integrity.";
RL J. Bacteriol. 199:E00606-E00606(2017).
CC -!- FUNCTION: Component of a transport pathway that contributes to membrane
CC integrity. {ECO:0000269|PubMed:27795327}.
CC -!- SUBUNIT: May form a complex with YebT. {ECO:0000305|PubMed:27795327}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000269|PubMed:15919996,
CC ECO:0000269|PubMed:27795327}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:27795327}.
CC -!- INDUCTION: Induced by a defect in lipopolysaccharide molecules.
CC {ECO:0000269|PubMed:27795327}.
CC -!- SIMILARITY: Belongs to the PqiA family. {ECO:0000305}.
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DR EMBL; U00096; AAC74903.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA15641.1; -; Genomic_DNA.
DR PIR; A64945; A64945.
DR RefSeq; NP_416347.1; NC_000913.3.
DR RefSeq; WP_001207282.1; NZ_STEB01000009.1.
DR AlphaFoldDB; P0AD03; -.
DR BioGRID; 4260356; 204.
DR DIP; DIP-48172N; -.
DR IntAct; P0AD03; 2.
DR STRING; 511145.b1833; -.
DR TCDB; 9.A.69.1.2; the intermembrane phospholipid translocase (impl-t) family.
DR PaxDb; P0AD03; -.
DR PRIDE; P0AD03; -.
DR EnsemblBacteria; AAC74903; AAC74903; b1833.
DR EnsemblBacteria; BAA15641; BAA15641; BAA15641.
DR GeneID; 946353; -.
DR KEGG; ecj:JW1822; -.
DR KEGG; eco:b1833; -.
DR PATRIC; fig|1411691.4.peg.417; -.
DR EchoBASE; EB3775; -.
DR eggNOG; COG2995; Bacteria.
DR HOGENOM; CLU_041903_0_1_6; -.
DR OMA; WVMFDVY; -.
DR PhylomeDB; P0AD03; -.
DR BioCyc; EcoCyc:G7006-MON; -.
DR PRO; PR:P0AD03; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IDA:EcoCyc.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0009408; P:response to heat; IMP:EcoCyc.
DR InterPro; IPR007498; PqiA-like.
DR InterPro; IPR005219; PqiA-like_Ent.
DR Pfam; PF04403; PqiA; 2.
DR TIGRFAMs; TIGR00155; pqiA_fam; 1.
DR PROSITE; PS51008; MULTIHEME_CYTC; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..427
FT /note="Intermembrane transport protein YebS"
FT /id="PRO_0000169052"
FT TOPO_DOM 1..75
FT /note="Cytoplasmic"
FT /evidence="ECO:0000269|PubMed:27795327"
FT TRANSMEM 76..96
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 97..120
FT /note="Periplasmic"
FT /evidence="ECO:0000269|PubMed:27795327"
FT TRANSMEM 121..141
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 142..269
FT /note="Cytoplasmic"
FT /evidence="ECO:0000269|PubMed:27795327"
FT TRANSMEM 270..290
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 291..310
FT /note="Periplasmic"
FT /evidence="ECO:0000269|PubMed:27795327"
FT TRANSMEM 311..331
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 332..350
FT /note="Cytoplasmic"
FT /evidence="ECO:0000269|PubMed:27795327"
FT TRANSMEM 351..371
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 372..382
FT /note="Periplasmic"
FT /evidence="ECO:0000269|PubMed:27795327"
FT TRANSMEM 383..403
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 404..427
FT /note="Cytoplasmic"
FT /evidence="ECO:0000269|PubMed:15919996,
FT ECO:0000269|PubMed:27795327"
SQ SEQUENCE 427 AA; 48273 MW; B506E3533D88146B CRC64;
MALNTPQITP TKKITVRAIG EELPRGDYQR CPQCDMLFSL PEINSHQSAY CPRCQAKIRD
GRDWSLTRLA AMAFTMLLLM PFAWGEPLLH IWLLGIRIDA NVMQGIWQMT KQGDAITGSM
VFFCVIGAPL ILVTSIAYLW FGNRLGMNLR PVLLMLERLK EWVMLDIYLV GIGVASIKVQ
DYAHIQAGVG LFSFVALVIL TTVTLSHLNV EELWERFYPQ RPATRRDEKL RVCLGCHFTG
YPDQRGRCPR CHIPLRLRRR HSLQKCWAAL LASIVLLLPA NLLPISIIYL NGGRQEDTIL
SGIMSLASSN IAVAGIVFIA SILVPFTKVI VMFTLLLSIH FKCQQGLRTR ILLLRMVTWI
GRWSMLDLFV ISLTMSLINR DQILAFTMGP AAFYFGAAVI LTILAVEWLD SRLLWDAHES
GNARFDD
