YEBZ_ECOLI
ID YEBZ_ECOLI Reviewed; 290 AA.
AC P76278; Q2MB12;
DT 27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 130.
DE RecName: Full=Inner membrane protein YebZ;
GN Name=yebZ; OrderedLocusNames=b1840, JW1829;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [3]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the CopD family. {ECO:0000305}.
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DR EMBL; U00096; AAC74910.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE76544.1; -; Genomic_DNA.
DR PIR; H64945; H64945.
DR RefSeq; NP_416354.1; NC_000913.3.
DR RefSeq; WP_000879289.1; NZ_SSZK01000001.1.
DR AlphaFoldDB; P76278; -.
DR BioGRID; 4260359; 8.
DR STRING; 511145.b1840; -.
DR TCDB; 9.B.62.1.4; the copper resistance (copd) family.
DR PaxDb; P76278; -.
DR PRIDE; P76278; -.
DR EnsemblBacteria; AAC74910; AAC74910; b1840.
DR EnsemblBacteria; BAE76544; BAE76544; BAE76544.
DR GeneID; 947078; -.
DR KEGG; ecj:JW1829; -.
DR KEGG; eco:b1840; -.
DR PATRIC; fig|1411691.4.peg.410; -.
DR EchoBASE; EB3782; -.
DR eggNOG; COG1276; Bacteria.
DR HOGENOM; CLU_075540_1_0_6; -.
DR OMA; TMMRFSR; -.
DR PhylomeDB; P76278; -.
DR BioCyc; EcoCyc:G7013-MON; -.
DR PRO; PR:P76278; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0006825; P:copper ion transport; IEA:InterPro.
DR InterPro; IPR032694; CopC/D.
DR InterPro; IPR008457; Cu-R_CopD.
DR PANTHER; PTHR34820; PTHR34820; 1.
DR Pfam; PF05425; CopD; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..290
FT /note="Inner membrane protein YebZ"
FT /id="PRO_0000218127"
FT TOPO_DOM 1..10
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 11..31
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 32..49
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 50..70
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 71..89
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 90..110
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 111..117
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 118..138
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 139..151
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 152..172
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 173..195
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 217..222
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 223..243
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 244..260
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 261..281
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 282..290
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 290 AA; 32526 MW; C4E1C8D98DE9A8FA CRC64;
MLAFTWIALR FIHFTSLMLV FGFAMYGAWL APLTIRRLLA KRFLRLQQHA AVWSLISATA
MLAVQGGLMG TGWTDVFSPN IWQAVLQTQF GGIWLWQIVL ALVTLIVALM QPRNMPRLLF
MLTTAQFILL AGVGHATLNE GVTAKIHQTN HAIHLICAAA WFGGLLPVLW CMQLIKGRWR
HQAIQALMRF SWCGHFAVIG VLASGVLNAL LITGFPPTLT TYWGQLLLLK AILVMIMVVI
ALANRYVLVP RMRQDEDRAA PWFVWMTKLE WAIGAVVLVI ISLLATLEPF
