ID   YEC5_YEAST              Reviewed;        1188 AA.
AC   P39991; D3DLM3;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 122.
DE   RecName: Full=Uncharacterized protein YEL025C;
GN   OrderedLocusNames=YEL025C;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169868;
RA   Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E.,
RA   Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E.,
RA   Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S.,
RA   Hyman R.W., Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D.,
RA   Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X.,
RA   Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y.,
RA   Botstein D., Davis R.W.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome V.";
RL   Nature 387:78-81(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; U18530; AAB64502.1; -; Genomic_DNA.
DR   EMBL; BK006939; DAA07627.1; -; Genomic_DNA.
DR   PIR; S50434; S50434.
DR   RefSeq; NP_010889.1; NM_001178840.1.
DR   AlphaFoldDB; P39991; -.
DR   SMR; P39991; -.
DR   BioGRID; 36704; 24.
DR   MINT; P39991; -.
DR   STRING; 4932.YEL025C; -.
DR   PaxDb; P39991; -.
DR   PRIDE; P39991; -.
DR   EnsemblFungi; YEL025C_mRNA; YEL025C; YEL025C.
DR   GeneID; 856688; -.
DR   KEGG; sce:YEL025C; -.
DR   SGD; S000000751; YEL025C.
DR   VEuPathDB; FungiDB:YEL025C; -.
DR   eggNOG; ENOG502SAD7; Eukaryota.
DR   HOGENOM; CLU_007972_0_0_1; -.
DR   InParanoid; P39991; -.
DR   BioCyc; YEAST:G3O-30148-MON; -.
DR   PRO; PR:P39991; -.
DR   Proteomes; UP000002311; Chromosome V.
DR   RNAct; P39991; protein.
DR   GO; GO:0005737; C:cytoplasm; HDA:SGD.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; HDA:SGD.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   4: Predicted;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..1188
FT                   /note="Uncharacterized protein YEL025C"
FT                   /id="PRO_0000202609"
FT   TRANSMEM        73..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        878..898
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1089..1109
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   1188 AA;  136069 MW;  82C3F04D1F78AD3D CRC64;
     MARQDETDCK KLDSNSAFLP LCITSYRSKD EAEKLVSCLH HEGSYFLCFS YGLYTGTSNE
     LKAKVEFALD GPFVVNYATV PMFMSASFCH LLMFNDGSIK GFKCENNKFE IIYDSNVAPK
     LDTISLLTSS WLNASFEGVL YTCNKNISYD SDLHTLCTTI YSFDFREGIV ERFYATDGEE
     IISFDFISRE DLLDDATCTG KSHVYFLCLL KSCYSENLFL KEYNLAGKHG SRKFDLNEYR
     QYNLLPICDN EFCYMKVVCG HTIVVLTTNY TQIINIKASG LTNGAFFNNK GLPNVENYQF
     LKDSYDVIYE RSVILLTISD VYANKYTAKI HTRSLHRDHV LKELQWTKER VFKPPKHDLC
     DVILQLPREK YIAVTRINGV NFISKDHRGS KLEKVKSGPA YTNKVYLASQ VIGNKGTDID
     SLLLGGSFNS RRGFLEKKIL VYDKTLFKLV TSSKALVENV TDFWVTDLAL NGGDEFAYES
     GGLIYKNGIF LMDEPYDYGL FVSRTGKVLK AGMDGSTGEF RQVDFLQSNH NSSTMFCYPV
     QNSKLRISIL EAKSGFLRKK EEFFIHGLNS KESIVSCFSD GAEKYLFVIY LDGVFSVWNA
     NQKKVATSHP DYSFIAYDQL IKISWLSKKH KHDSIYVIAS SYTGCVRVYK SESNFLRVDL
     EIHSLYDQKL ELLDTIPSLP LVFLYNDKEI ILLNLQNMSY GCIQLGLVPR RMRIRPGKAL
     FSLCVLDYDS RISIFEFGST FYREGFTKQM TSLKPQLENH IFYLPSIPVE LYTVPNNLNQ
     AVVCLVDSNS RQYKLMLFNY ASMKAVSTFS FSDEKYLHAV VKPLWPEQNS IYLSQRPFYG
     NKFVVCLGVG EKRTKFWLFE IRNNNITQLY ANYLEDCIFS VFIYYECNLV LFSGDSGIAA
     YKINMLKEGA EILEAYSFPA LSSINHIGLP AYMSGDYLVQ FEILRDFLRT RFPIRTSIVY
     PSEYPECPYL GFKRLGSITQ VATKIIPKKL REPKNDCLAS DKNYLLGRLS DLSCATLKYS
     NRSYVATIGI DNTLTIYEDS KLSVDKGGLA MPYLKIRLPN KIISLAAIPD GFQNLQICPN
     FNSQRLEGVI PLFLLCGTEG QIYIISEFIG ELWMRTLHDY KKIKLECKRA FRRSEKSMRN
     VTKQYSVSKE TGINESGFDE LARNSKRRHI DHSPYKTIDF FDPVKLKR