YEC6_SCHPO
ID YEC6_SCHPO Reviewed; 408 AA.
AC Q9Y825;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Uncharacterized WD repeat-containing protein C25H1.06;
GN ORFNames=SPAC25H1.06;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329670; CAB11602.1; -; Genomic_DNA.
DR PIR; T38386; T38386.
DR RefSeq; NP_593810.1; NM_001019239.2.
DR AlphaFoldDB; Q9Y825; -.
DR SMR; Q9Y825; -.
DR BioGRID; 278152; 27.
DR STRING; 4896.SPAC25H1.06.1; -.
DR SwissPalm; Q9Y825; -.
DR MaxQB; Q9Y825; -.
DR PaxDb; Q9Y825; -.
DR PRIDE; Q9Y825; -.
DR EnsemblFungi; SPAC25H1.06.1; SPAC25H1.06.1:pep; SPAC25H1.06.
DR GeneID; 2541656; -.
DR KEGG; spo:SPAC25H1.06; -.
DR PomBase; SPAC25H1.06; -.
DR VEuPathDB; FungiDB:SPAC25H1.06; -.
DR eggNOG; KOG0264; Eukaryota.
DR HOGENOM; CLU_020445_3_1_1; -.
DR InParanoid; Q9Y825; -.
DR OMA; DNELHIW; -.
DR PhylomeDB; Q9Y825; -.
DR Reactome; R-SPO-3214815; HDACs deacetylate histones.
DR Reactome; R-SPO-3214847; HATs acetylate histones.
DR Reactome; R-SPO-8951664; Neddylation.
DR PRO; PR:Q9Y825; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0033186; C:CAF-1 complex; IDA:PomBase.
DR GO; GO:0000785; C:chromatin; IC:PomBase.
DR GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0043596; C:nuclear replication fork; IPI:PomBase.
DR GO; GO:0005634; C:nucleus; IDA:PomBase.
DR GO; GO:0042393; F:histone binding; IBA:GO_Central.
DR GO; GO:0006338; P:chromatin remodeling; IBA:GO_Central.
DR GO; GO:0006335; P:DNA replication-dependent chromatin assembly; IC:PomBase.
DR GO; GO:1990426; P:mitotic recombination-dependent replication fork processing; IDA:PomBase.
DR Gene3D; 2.130.10.10; -; 1.
DR InterPro; IPR022052; Histone-bd_RBBP4_N.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR Pfam; PF12265; CAF1C_H4-bd; 1.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Cytoplasm; Reference proteome; Repeat; WD repeat.
FT CHAIN 1..408
FT /note="Uncharacterized WD repeat-containing protein
FT C25H1.06"
FT /id="PRO_0000316553"
FT REPEAT 129..169
FT /note="WD 1"
FT REPEAT 180..220
FT /note="WD 2"
FT REPEAT 230..269
FT /note="WD 3"
FT REPEAT 273..312
FT /note="WD 4"
FT REPEAT 330..369
FT /note="WD 5"
FT REPEAT 371..408
FT /note="WD 6"
SQ SEQUENCE 408 AA; 46796 MW; 3C21029D9143F76E CRC64;
MNTELDMQNF EHIKFLENQI SEDHFRWKKN SKHLYNLLIT RTLTWPSLSI QWLSAMESIT
EKAVLKNRLL LGTHAAEGMP NFLQLADLDL PDFNQTILDP VKHYNEDTGE LGGYSMQHSC
KFQISQRILH NGDVNRVRHM PQNPNIIATM SSCGNAYIFD RTKYTSMPAE EFLPNISLIG
HKKEGFGLSW NRQQNCRLVT AANDSKILEW DLNNFSRDTR CLTPVKDFHY DDSPVNDVEY
HPHHTNLYIA VNDNGIAFIC DNRLQQTCSK TVKASNPLFS VRHNPSIATL FALGSEQDLQ
LWDLRNLNKS VFNTSEDLSD NRLKVPSRLT LGGTSLSWSW RHSGRIVSAC QEYCYVWNFN
KANPLEFVHA GHKGTVNEVD FDPFEAQCIA SVADDNELHI WKPNVIVN