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YEC8_SCHPO
ID   YEC8_SCHPO              Reviewed;         399 AA.
AC   O13982;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 139.
DE   RecName: Full=Uncharacterized WD repeat-containing protein C25H1.08c;
GN   ORFNames=SPAC25H1.08c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC       {ECO:0000269|PubMed:16823372}.
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DR   EMBL; CU329670; CAB11604.1; -; Genomic_DNA.
DR   PIR; T38388; T38388.
DR   RefSeq; NP_593812.1; NM_001019241.2.
DR   AlphaFoldDB; O13982; -.
DR   SMR; O13982; -.
DR   BioGRID; 279168; 4.
DR   STRING; 4896.SPAC25H1.08c.1; -.
DR   iPTMnet; O13982; -.
DR   MaxQB; O13982; -.
DR   PaxDb; O13982; -.
DR   EnsemblFungi; SPAC25H1.08c.1; SPAC25H1.08c.1:pep; SPAC25H1.08c.
DR   GeneID; 2542715; -.
DR   KEGG; spo:SPAC25H1.08c; -.
DR   PomBase; SPAC25H1.08c; -.
DR   VEuPathDB; FungiDB:SPAC25H1.08c; -.
DR   eggNOG; KOG0296; Eukaryota.
DR   HOGENOM; CLU_000288_57_9_1; -.
DR   InParanoid; O13982; -.
DR   OMA; WMWKVPS; -.
DR   PhylomeDB; O13982; -.
DR   PRO; PR:O13982; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0030687; C:preribosome, large subunit precursor; ISO:PomBase.
DR   GO; GO:0000027; P:ribosomal large subunit assembly; ISO:PomBase.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR024977; Apc4_WD40_dom.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF12894; ANAPC4_WD40; 1.
DR   Pfam; PF00400; WD40; 3.
DR   SMART; SM00320; WD40; 8.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 5.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   4: Predicted;
KW   Cytoplasm; Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..399
FT                   /note="Uncharacterized WD repeat-containing protein
FT                   C25H1.08c"
FT                   /id="PRO_0000316554"
FT   REPEAT          59..99
FT                   /note="WD 1"
FT   REPEAT          102..141
FT                   /note="WD 2"
FT   REPEAT          144..185
FT                   /note="WD 3"
FT   REPEAT          187..227
FT                   /note="WD 4"
FT   REPEAT          241..280
FT                   /note="WD 5"
FT   REPEAT          283..322
FT                   /note="WD 6"
FT   REPEAT          324..363
FT                   /note="WD 7"
FT   REPEAT          366..399
FT                   /note="WD 8"
SQ   SEQUENCE   399 AA;  43432 MW;  B536BD0A088D037F CRC64;
     MAEEEENQEL YIAENEVEEV IKDNDKLMDQ GVTEDEAEQE QNDTMNNMVM DMSVQGFFEH
     KDSVFSVSIN PVHSNLCASG GGDDLGYIWD ITTGEQICQL TGHKDSIVAI DWSFDGTYIA
     TGGMDSQVRL WKSSTGFEFI TAFETVDEIV WLSWHPKGLF LAAGCNDGSI WMWSLPSGKV
     VQVMYGHTAP VNAGKFIPPG VGKRLATVDD SGTLIVWNPA TGAPECRMSS DDHRFDPGNE
     ETAAGWTSFD CNAEGNVLFL GGSSGKVKVV NINSSHILAS LEAQTESVEA IALCTALPIC
     ACASVDGTVA LYDSASLKFR KSLPHEQAVI DCKFLPNTPY LLTACADCVI RKWDVRSGQL
     LGEYTGHQEP ILCMAITPDG KRVVTGSDDT ELLVFDCEH
 
 
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