ID   YEDE_ECOLI              Reviewed;         401 AA.
AC   P31064;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   03-AUG-2022, entry version 141.
DE   RecName: Full=UPF0394 inner membrane protein YedE;
GN   Name=yedE; OrderedLocusNames=b1929, JW1914;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=JA11;
RX   PubMed=8371104; DOI=10.1099/00221287-139-7-1401;
RA   Raha M., Kihara M., Kawagishi I., Macnab R.M.;
RT   "Organization of the Escherichia coli and Salmonella typhimurium
RT   chromosomes between flagellar regions IIIa and IIIb, including a large non-
RT   coding region.";
RL   J. Gen. Microbiol. 139:1401-1407(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9097040; DOI=10.1093/dnares/3.6.379;
RA   Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K.,
RA   Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T.,
RA   Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S., Nakamura Y.,
RA   Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y.,
RA   Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y.,
RA   Horiuchi T.;
RT   "A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 40.1-50.0 min region on the linkage map.";
RL   DNA Res. 3:379-392(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   TOPOLOGY [LARGE SCALE ANALYSIS].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=15919996; DOI=10.1126/science.1109730;
RA   Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT   "Global topology analysis of the Escherichia coli inner membrane
RT   proteome.";
RL   Science 308:1321-1323(2005).
CC   -!- INTERACTION:
CC       P31064; P15770: aroE; NbExp=2; IntAct=EBI-544094, EBI-544087;
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the UPF0394 family. {ECO:0000305}.
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DR   EMBL; L13279; AAA82577.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC74996.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA15757.1; -; Genomic_DNA.
DR   PIR; F64956; F64956.
DR   RefSeq; NP_416439.1; NC_000913.3.
DR   RefSeq; WP_000118897.1; NZ_SSUR01000001.1.
DR   AlphaFoldDB; P31064; -.
DR   BioGRID; 4261058; 171.
DR   DIP; DIP-11839N; -.
DR   IntAct; P31064; 1.
DR   STRING; 511145.b1929; -.
DR   TCDB; 9.B.102.1.1; the yede/yeee (yede/yeee) family.
DR   jPOST; P31064; -.
DR   PaxDb; P31064; -.
DR   PRIDE; P31064; -.
DR   EnsemblBacteria; AAC74996; AAC74996; b1929.
DR   EnsemblBacteria; BAA15757; BAA15757; BAA15757.
DR   GeneID; 945192; -.
DR   KEGG; ecj:JW1914; -.
DR   KEGG; eco:b1929; -.
DR   PATRIC; fig|1411691.4.peg.320; -.
DR   EchoBASE; EB1612; -.
DR   eggNOG; COG2391; Bacteria.
DR   HOGENOM; CLU_041737_0_0_6; -.
DR   InParanoid; P31064; -.
DR   OMA; FFTGIPM; -.
DR   PhylomeDB; P31064; -.
DR   BioCyc; EcoCyc:EG11660-MON; -.
DR   PRO; PR:P31064; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; ISM:EcoCyc.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR   InterPro; IPR007272; Sulf_transp.
DR   Pfam; PF04143; Sulf_transp; 2.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..401
FT                   /note="UPF0394 inner membrane protein YedE"
FT                   /id="PRO_0000169090"
FT   TOPO_DOM        1..13
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        35..78
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        79..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        100..111
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        112..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        133
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        155..198
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        199..219
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        220..259
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        260..280
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        281..283
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        284..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        305..363
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        364..384
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        385..401
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   401 AA;  44429 MW;  E07554C206B367E4 CRC64;
     MSWQQFKHAW LIKFWAPIPA VIAAGILSTY YFGITGTFWA VTGEFTRWGG QLLQLFGVHA
     EEWGYFKIIH LEGSPLTRID GMMILGMFGG CFAAALWANN VKLRMPRSRI RIMQAIIGGI
     IAGFGARLAM GCNLAAFFTG IPQFSLHAWF FAIATAIGSW FGARFTLLPI FRIPVKMQKV
     SAASPLTQKP DQARRRFRLG MLVFFGMLGW ALLTAMNQPK LGLAMLFGVG FGLLIERAQI
     CFTSAFRDMW ITGRTHMAKA IIIGMAVSAI GIFSYVQLGV EPKIMWAGPN AVIGGLLFGF
     GIVLAGGCET GWMYRAVEGQ VHYWWVGLGN VIGSTILAYY WDDFAPALAT DWDKINLLKT
     FGPMGGLLVT YLLLFAALML IIGWEKRFFR RAAPQTAKEI A