YEEA_ECOLI
ID YEEA_ECOLI Reviewed; 352 AA.
AC P33011; P76368;
DT 01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 2.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Inner membrane protein YeeA;
GN Name=yeeA; OrderedLocusNames=b2008, JW1990;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097040; DOI=10.1093/dnares/3.6.379;
RA Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K.,
RA Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T.,
RA Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S., Nakamura Y.,
RA Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y.,
RA Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y.,
RA Horiuchi T.;
RT "A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 40.1-50.0 min region on the linkage map.";
RL DNA Res. 3:379-392(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 1-149.
RC STRAIN=K12 / BHB2600;
RA Richterich P., Lakey N., Gryan G., Jaehn L., Mintz L., Robison K.,
RA Church G.M.;
RT "Automated multiplex sequencing of the E.coli genome.";
RL Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
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DR EMBL; U00096; AAC75069.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA15829.1; -; Genomic_DNA.
DR EMBL; U00009; AAA16414.1; -; Genomic_DNA.
DR PIR; G64965; G64965.
DR RefSeq; NP_416512.1; NC_000913.3.
DR RefSeq; WP_001200891.1; NZ_SSTT01000011.1.
DR AlphaFoldDB; P33011; -.
DR SMR; P33011; -.
DR BioGRID; 4261061; 23.
DR STRING; 511145.b2008; -.
DR TCDB; 2.A.85.7.1; the aromatic acid exporter (arae) family.
DR jPOST; P33011; -.
DR PaxDb; P33011; -.
DR PRIDE; P33011; -.
DR EnsemblBacteria; AAC75069; AAC75069; b2008.
DR EnsemblBacteria; BAA15829; BAA15829; BAA15829.
DR GeneID; 58459717; -.
DR GeneID; 946545; -.
DR KEGG; ecj:JW1990; -.
DR KEGG; eco:b2008; -.
DR PATRIC; fig|1411691.4.peg.244; -.
DR EchoBASE; EB1837; -.
DR eggNOG; COG1289; Bacteria.
DR HOGENOM; CLU_064722_0_0_6; -.
DR OMA; PHGEWAS; -.
DR PhylomeDB; P33011; -.
DR BioCyc; EcoCyc:EG11891-MON; -.
DR PRO; PR:P33011; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR InterPro; IPR006726; PHBA_efflux_AaeB/fusaric-R.
DR Pfam; PF04632; FUSC; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..352
FT /note="Inner membrane protein YeeA"
FT /id="PRO_0000169106"
FT TOPO_DOM 1..25
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 26..46
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 68
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 90
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 91..111
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 112..117
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 118..138
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 139..147
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 148..168
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 169..352
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 352 AA; 39955 MW; E57438065D8E2AA2 CRC64;
MRADKSLSPF EIRVYRHYRI VHGTRVALAF LLTFLIIRLF TIPESTWPLV TMVVIMGPIS
FWGNVVPRAF ERIGGTVLGS ILGLIALQLE LISLPLMLVW CAAAMFLCGW LALGKKPYQG
LLIGVTLAIV VGSPTGEIDT ALWRSGDVIL GSLLAMLFTG IWPQRAFIHW RIQLAKSLTE
YNRVYQSAFS PNLLERPRLE SHLQKLLTDA VKMRGLIAPA SKETRIPKSI YEGIQTINRN
LVCMLELQIN AYWATRPSHF VLLNAQKLRD TQHMMQQILL SLVHALYEGN PQPVFANTEK
LNDAVEELRQ LLNNHHDLKV VETPIYGYVW LNMETAHQLE LLSNLICRAL RK
