ID   YEFM_MYCBO              Reviewed;          91 AA.
AC   P65068; A0A1R3Y3Z1; O50386; X2BN90;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Antitoxin YefM;
GN   Name=yefM; OrderedLocusNames=BQ2027_MB3392;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- FUNCTION: Antitoxin component of a type II toxin-antitoxin (TA) system.
CC       A probable antitoxin for the putative mRNA interferase YeoB (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. May form YefM(2)-YoeB toxin-antitoxin complexes
CC       which inhibits the toxins activity (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the phD/YefM antitoxin family. {ECO:0000305}.
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DR   EMBL; LT708304; SIU02021.1; -; Genomic_DNA.
DR   RefSeq; NP_857033.1; NC_002945.3.
DR   RefSeq; WP_003417757.1; NC_002945.4.
DR   AlphaFoldDB; P65068; -.
DR   SMR; P65068; -.
DR   EnsemblBacteria; SIU02021; SIU02021; BQ2027_MB3392.
DR   GeneID; 45427356; -.
DR   PATRIC; fig|233413.5.peg.3727; -.
DR   OMA; SIMETNY; -.
DR   Proteomes; UP000001419; Chromosome.
DR   InterPro; IPR006442; Antitoxin_Phd/YefM.
DR   InterPro; IPR036165; YefM-like_sf.
DR   Pfam; PF02604; PhdYeFM_antitox; 1.
DR   SUPFAM; SSF143120; SSF143120; 1.
PE   3: Inferred from homology;
KW   Toxin-antitoxin system.
FT   CHAIN           1..91
FT                   /note="Antitoxin YefM"
FT                   /id="PRO_0000213741"
SQ   SEQUENCE   91 AA;  10194 MW;  5A4140972F329F0A CRC64;
     MSISASEARQ RLFPLIEQVN TDHQPVRITS RAGDAVLMSA DDYDAWQETV YLLRSPENAR
     RLMEAVARDK AGHSAFTKSV DELREMAGGE E