ID   YEFM_SALTY              Reviewed;          75 AA.
AC   P40819;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   13-DEC-2001, sequence version 2.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Orphan antitoxin YefM;
GN   Name=yefM; Synonyms=yhhV; OrderedLocusNames=STM3559;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-68.
RC   STRAIN=LT2;
RX   PubMed=1429514; DOI=10.1093/oxfordjournals.jbchem.a123872;
RA   Matsubara K., Ohnishi K., Kiritani K.;
RT   "Nucleotide sequences and characterization of liv genes encoding components
RT   of the high-affinity branched-chain amino acid transport system in
RT   Salmonella typhimurium.";
RL   J. Biochem. 112:93-101(1992).
RN   [3]
RP   IDENTIFICATION.
RX   PubMed=7920643; DOI=10.1038/ng0694-205;
RA   Robison K., Gilbert W., Church G.M.;
RT   "Large scale bacterial gene discovery by similarity search.";
RL   Nat. Genet. 7:205-214(1994).
CC   -!- FUNCTION: Putative antitoxin component of a toxin-antitoxin (TA)
CC       system; its cognate toxin is unknown.
CC   -!- SIMILARITY: Belongs to the phD/YefM antitoxin family. {ECO:0000305}.
CC   -!- CAUTION: YoeB, the specific toxin against which this antitoxin acts in
CC       E.coli, is not encoded in this genome. {ECO:0000305}.
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DR   EMBL; AE006468; AAL22419.1; -; Genomic_DNA.
DR   EMBL; D12589; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_462460.1; NC_003197.2.
DR   RefSeq; WP_000481005.1; NC_003197.2.
DR   AlphaFoldDB; P40819; -.
DR   SMR; P40819; -.
DR   STRING; 99287.STM3559; -.
DR   PaxDb; P40819; -.
DR   DNASU; 1255082; -.
DR   EnsemblBacteria; AAL22419; AAL22419; STM3559.
DR   GeneID; 1255082; -.
DR   KEGG; stm:STM3559; -.
DR   PATRIC; fig|99287.12.peg.3762; -.
DR   HOGENOM; CLU_193635_0_0_6; -.
DR   OMA; HGNEIRE; -.
DR   PhylomeDB; P40819; -.
DR   BioCyc; SENT99287:STM3559-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   CollecTF; EXPREG_00000a90; -.
DR   GO; GO:0032993; C:protein-DNA complex; IMP:CollecTF.
DR   GO; GO:0001217; F:DNA-binding transcription repressor activity; IMP:CollecTF.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IMP:CollecTF.
DR   InterPro; IPR006442; Antitoxin_Phd/YefM.
DR   InterPro; IPR036165; YefM-like_sf.
DR   Pfam; PF02604; PhdYeFM_antitox; 1.
DR   SUPFAM; SSF143120; SSF143120; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Toxin-antitoxin system.
FT   CHAIN           1..75
FT                   /note="Orphan antitoxin YefM"
FT                   /id="PRO_0000213744"
SQ   SEQUENCE   75 AA;  8431 MW;  8396A4A40B28D314 CRC64;
     MFMRTVNYSE ARQNLAEVLE SAVTGGPVTI TRRGHKSAVI ISAEEFERYQ TARMDDEFAA
     IMAVHGNELR ELADK