ID   YEFM_SYNY3              Reviewed;          87 AA.
AC   P58235;
DT   14-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   14-AUG-2001, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=Antitoxin YefM;
GN   Name=yefM; OrderedLocusNames=ssr2754;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27184 / PCC 6803 / N-1;
RX   PubMed=8590279; DOI=10.1093/dnares/2.4.153;
RA   Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N.,
RA   Sugiura M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region
RT   from map positions 64% to 92% of the genome.";
RL   DNA Res. 2:153-166(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
CC   -!- FUNCTION: Antitoxin component of a type II toxin-antitoxin (TA) system.
CC       A probable antitoxin for the putative mRNA interferase YeoB (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Forms a complex with YoeB which inhibits its toxin activity.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the phD/YefM antitoxin family. {ECO:0000305}.
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DR   EMBL; BA000022; BAB61866.1; -; Genomic_DNA.
DR   AlphaFoldDB; P58235; -.
DR   SMR; P58235; -.
DR   IntAct; P58235; 1.
DR   STRING; 1148.14595112; -.
DR   PaxDb; P58235; -.
DR   EnsemblBacteria; BAB61866; BAB61866; BAB61866.
DR   KEGG; syn:ssr2754; -.
DR   eggNOG; COG2161; Bacteria.
DR   InParanoid; P58235; -.
DR   OMA; VEPTIIC; -.
DR   PhylomeDB; P58235; -.
DR   Proteomes; UP000001425; Chromosome.
DR   InterPro; IPR006442; Antitoxin_Phd/YefM.
DR   InterPro; IPR036165; YefM-like_sf.
DR   Pfam; PF02604; PhdYeFM_antitox; 1.
DR   SUPFAM; SSF143120; SSF143120; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Toxin-antitoxin system.
FT   CHAIN           1..87
FT                   /note="Antitoxin YefM"
FT                   /id="PRO_0000213745"
SQ   SEQUENCE   87 AA;  9688 MW;  C98878B18CC1A254 CRC64;
     MKAITTTQAK DHLDELINAV ISDLEPTIVS NNQGQQAVLI SLDEFNSWQE TLYLLSNPTN
     AEHLMASIKQ AETGQIIKQK LPDLLEL