YEG3_SCHPO
ID YEG3_SCHPO Reviewed; 512 AA.
AC O13985;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1999, sequence version 2.
DT 25-MAY-2022, entry version 146.
DE RecName: Full=Uncharacterized WD repeat-containing protein C26H5.03;
GN ORFNames=SPAC26H5.03;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-468; SER-470 AND SER-473, AND
RP IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- INTERACTION:
CC O13985; Q1MTN9: rlf2; NbExp=2; IntAct=EBI-16123749, EBI-1560762;
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329670; CAB16189.1; -; Genomic_DNA.
DR PIR; T38422; T38422.
DR RefSeq; NP_594450.1; NM_001019879.2.
DR PDB; 2Z3F; X-ray; 2.70 A; I/J/K/L/M/N/O/P/Q/R/T=493-512.
DR PDBsum; 2Z3F; -.
DR AlphaFoldDB; O13985; -.
DR SMR; O13985; -.
DR BioGRID; 278548; 44.
DR DIP; DIP-61057N; -.
DR IntAct; O13985; 2.
DR STRING; 4896.SPAC26H5.03.1; -.
DR iPTMnet; O13985; -.
DR MaxQB; O13985; -.
DR PaxDb; O13985; -.
DR PRIDE; O13985; -.
DR EnsemblFungi; SPAC26H5.03.1; SPAC26H5.03.1:pep; SPAC26H5.03.
DR GeneID; 2542071; -.
DR KEGG; spo:SPAC26H5.03; -.
DR PomBase; SPAC26H5.03; -.
DR VEuPathDB; FungiDB:SPAC26H5.03; -.
DR eggNOG; KOG1009; Eukaryota.
DR HOGENOM; CLU_010127_0_0_1; -.
DR InParanoid; O13985; -.
DR OMA; CTIAVRC; -.
DR PhylomeDB; O13985; -.
DR EvolutionaryTrace; O13985; -.
DR PRO; PR:O13985; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0033186; C:CAF-1 complex; IDA:PomBase.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0043596; C:nuclear replication fork; IDA:PomBase.
DR GO; GO:0005634; C:nucleus; IDA:PomBase.
DR GO; GO:0006335; P:DNA replication-dependent chromatin assembly; IC:PomBase.
DR GO; GO:1990426; P:mitotic recombination-dependent replication fork processing; IDA:PomBase.
DR GO; GO:0006334; P:nucleosome assembly; IBA:GO_Central.
DR Gene3D; 2.130.10.10; -; 2.
DR IDEAL; IID50257; -.
DR InterPro; IPR024977; Apc4_WD40_dom.
DR InterPro; IPR045145; PTHR15271.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR15271; PTHR15271; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cytoplasm; Nucleus; Phosphoprotein; Reference proteome;
KW Repeat; WD repeat.
FT CHAIN 1..512
FT /note="Uncharacterized WD repeat-containing protein
FT C26H5.03"
FT /id="PRO_0000316555"
FT REPEAT 16..56
FT /note="WD 1"
FT REPEAT 65..105
FT /note="WD 2"
FT REPEAT 126..165
FT /note="WD 3"
FT REPEAT 168..207
FT /note="WD 4"
FT REPEAT 373..413
FT /note="WD 5"
FT REPEAT 417..458
FT /note="WD 6"
FT REGION 238..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 459..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 464..495
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 468
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT MOD_RES 470
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT MOD_RES 473
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT STRAND 508..511
FT /evidence="ECO:0007829|PDB:2Z3F"
SQ SEQUENCE 512 AA; 57426 MW; 6010733FED6CC87C CRC64;
MRAEVLQIRW HYDANDDHTP IYSVDFQKNS LNKFATCGGD SKIRIWQLIT SESSTKVEYL
STLSRHTQAV NVVRFNPEGN ILATAGDEGT IMLWVPTNTP ITTLADDAEE LALAKEYWKV
KIVCRSMGSE IYDLCWSVDS NFLIAGAMDN SLRLYDAHTG QLLTQKFDHS HYVQGVCWDP
LNQYIVSESS DRSICLYEIQ EEKKNPKKFQ LVLKSRICRI EYNVTKFELI SVTKPLNNDE
SSGISEPIET SNNNESPVSK HEALSSTANI VKDGSLERTE PPNSLNSKIS YSLYCNETLV
SFFRRPAFSP DGLLLVTPAG RLRPHGQPNF EVPYTAYIYT RGSITKQPVA CLNGFKKPVI
AVRFSPIHYE LNSFSNFSFT SVSFNLPYRM VFAVACQDAV YIYDTQTCKP FYRAVNLHYS
NLTDIAWNDD GNVLLMTSID GFCSVITFEP GELGVKSQHK ISLPEKRSAS PSSIDDSQDN
TAGGPATTTL IPRKVESSKV SKKRIAPTPV YP
