ID   YEGW_ECOL6              Reviewed;         248 AA.
AC   P0ACM6; O08014; P76420;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator YegW;
GN   Name=yegW; OrderedLocusNames=c2628;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
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DR   EMBL; AE014075; AAN81084.1; -; Genomic_DNA.
DR   RefSeq; WP_000434038.1; NC_004431.1.
DR   AlphaFoldDB; P0ACM6; -.
DR   SMR; P0ACM6; -.
DR   STRING; 199310.c2628; -.
DR   EnsemblBacteria; AAN81084; AAN81084; c2628.
DR   GeneID; 66674003; -.
DR   KEGG; ecc:c2628; -.
DR   eggNOG; COG2188; Bacteria.
DR   HOGENOM; CLU_063236_4_0_6; -.
DR   OMA; DRYKFVA; -.
DR   BioCyc; ECOL199310:C2628-MON; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.40.1410.10; -; 1.
DR   InterPro; IPR028978; Chorismate_lyase_/UTRA_dom_sf.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR011663; UTRA.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00392; GntR; 1.
DR   Pfam; PF07702; UTRA; 1.
DR   PRINTS; PR00035; HTHGNTR.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SMART; SM00866; UTRA; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF64288; SSF64288; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   4: Predicted;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..248
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   YegW"
FT                   /id="PRO_0000050678"
FT   DOMAIN          22..90
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
FT   DNA_BIND        50..69
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
SQ   SEQUENCE   248 AA;  28277 MW;  E4B3CD729CA7F1C8 CRC64;
     MEQAHTQLIA QLNERILAAD NTPLYIKFAE TVKNAVRSGV LEHGNILPGE RDLSQLTGVS
     RITVRKAMQA LEEEGVVTRS RGYGTQINNI FEYSLKEARG FSQQVVLRGK KPDTLWVNKR
     VVKCPEEVAQ QLAVEAGSDV FLLKRIRYVD EEAVSIEESW VPAHLIHDVD AIGISLYDYF
     RSQHIYPQRT RSRVSARMPD AEFQSHIQLD SKIPVLVIKQ VALDQQQRPI EYSISHCRSD
     LYVFVCEE