ID   YEGW_SHIFL              Reviewed;         248 AA.
AC   P0ACM8; O08014; P76420;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator YegW;
GN   Name=yegW; OrderedLocusNames=S2288;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
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DR   EMBL; AE014073; AAP17520.1; -; Genomic_DNA.
DR   RefSeq; WP_000434038.1; NZ_WHSI01000027.1.
DR   AlphaFoldDB; P0ACM8; -.
DR   SMR; P0ACM8; -.
DR   DNASU; 1077931; -.
DR   EnsemblBacteria; AAP17520; AAP17520; S2288.
DR   GeneID; 66674003; -.
DR   KEGG; sfx:S2288; -.
DR   PATRIC; fig|623.156.peg.3728; -.
DR   HOGENOM; CLU_063236_4_0_6; -.
DR   OMA; DRYKFVA; -.
DR   OrthoDB; 1775418at2; -.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.40.1410.10; -; 1.
DR   InterPro; IPR028978; Chorismate_lyase_/UTRA_dom_sf.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR011663; UTRA.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00392; GntR; 1.
DR   Pfam; PF07702; UTRA; 1.
DR   PRINTS; PR00035; HTHGNTR.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SMART; SM00866; UTRA; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF64288; SSF64288; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   4: Predicted;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..248
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   YegW"
FT                   /id="PRO_0000050679"
FT   DOMAIN          22..90
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
FT   DNA_BIND        50..69
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
SQ   SEQUENCE   248 AA;  28277 MW;  E4B3CD729CA7F1C8 CRC64;
     MEQAHTQLIA QLNERILAAD NTPLYIKFAE TVKNAVRSGV LEHGNILPGE RDLSQLTGVS
     RITVRKAMQA LEEEGVVTRS RGYGTQINNI FEYSLKEARG FSQQVVLRGK KPDTLWVNKR
     VVKCPEEVAQ QLAVEAGSDV FLLKRIRYVD EEAVSIEESW VPAHLIHDVD AIGISLYDYF
     RSQHIYPQRT RSRVSARMPD AEFQSHIQLD SKIPVLVIKQ VALDQQQRPI EYSISHCRSD
     LYVFVCEE