YEHA_ECOLI
ID YEHA_ECOLI Reviewed; 344 AA.
AC P33340;
DT 01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1994, sequence version 1.
DT 03-AUG-2022, entry version 129.
DE RecName: Full=Uncharacterized fimbrial-like protein YehA;
DE Flags: Precursor;
GN Name=yehA; OrderedLocusNames=b2108, JW2095;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / BHB2600;
RA Richterich P., Lakey N., Gryan G., Jaehn L., Mintz L., Robison K.,
RA Church G.M.;
RT "Automated multiplex sequencing of the E.coli genome.";
RL Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097040; DOI=10.1093/dnares/3.6.379;
RA Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K.,
RA Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T.,
RA Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S., Nakamura Y.,
RA Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y.,
RA Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y.,
RA Horiuchi T.;
RT "A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 40.1-50.0 min region on the linkage map.";
RL DNA Res. 3:379-392(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP FUNCTION, INDUCTION, AND DISRUPTION PHENOTYPE.
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=20345943; DOI=10.1111/j.1462-2920.2010.02202.x;
RA Korea C.G., Badouraly R., Prevost M.C., Ghigo J.M., Beloin C.;
RT "Escherichia coli K-12 possesses multiple cryptic but functional chaperone-
RT usher fimbriae with distinct surface specificities.";
RL Environ. Microbiol. 12:1957-1977(2010).
CC -!- FUNCTION: Part of the yehABCD fimbrial operon. Could contribute to
CC adhesion to various surfaces in specific environmental niches.
CC {ECO:0000269|PubMed:20345943}.
CC -!- INDUCTION: Expression is negatively regulated by H-NS and subjected to
CC cAMP receptor protein (CRP)-mediated catabolite repression.
CC {ECO:0000269|PubMed:20345943}.
CC -!- DISRUPTION PHENOTYPE: Deletion of the operon under classical laboratory
CC conditions does not result in any major effect on E.coli capacity to
CC form biofilms compared with the wild-type strain.
CC {ECO:0000269|PubMed:20345943}.
CC -!- MISCELLANEOUS: The operon is cryptic under classical laboratory
CC conditions, but is functional when constitutively expressed.
CC {ECO:0000305|PubMed:20345943}.
CC -!- SIMILARITY: Belongs to the fimbrial protein family. {ECO:0000305}.
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DR EMBL; U00007; AAA60472.1; -; Genomic_DNA.
DR EMBL; U00096; AAC75169.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA15974.1; -; Genomic_DNA.
DR PIR; C64978; C64978.
DR RefSeq; NP_416611.1; NC_000913.3.
DR RefSeq; WP_000405713.1; NZ_SSZK01000011.1.
DR AlphaFoldDB; P33340; -.
DR SMR; P33340; -.
DR BioGRID; 4260434; 10.
DR IntAct; P33340; 1.
DR STRING; 511145.b2108; -.
DR PaxDb; P33340; -.
DR PRIDE; P33340; -.
DR EnsemblBacteria; AAC75169; AAC75169; b2108.
DR EnsemblBacteria; BAA15974; BAA15974; BAA15974.
DR GeneID; 946642; -.
DR KEGG; ecj:JW2095; -.
DR KEGG; eco:b2108; -.
DR PATRIC; fig|1411691.4.peg.139; -.
DR EchoBASE; EB1930; -.
DR eggNOG; COG3539; Bacteria.
DR HOGENOM; CLU_069559_0_0_6; -.
DR OMA; IVLRCKN; -.
DR PhylomeDB; P33340; -.
DR BioCyc; EcoCyc:EG11987-MON; -.
DR PRO; PR:P33340; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0009289; C:pilus; IEA:InterPro.
DR GO; GO:0043709; P:cell adhesion involved in single-species biofilm formation; IMP:EcoCyc.
DR Gene3D; 2.60.40.1090; -; 1.
DR InterPro; IPR000259; Adhesion_dom_fimbrial.
DR InterPro; IPR036937; Adhesion_dom_fimbrial_sf.
DR InterPro; IPR008966; Adhesion_dom_sf.
DR InterPro; IPR016959; UCP030811.
DR Pfam; PF00419; Fimbrial; 1.
DR PIRSF; PIRSF030811; UCP030811; 1.
DR SUPFAM; SSF49401; SSF49401; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..344
FT /note="Uncharacterized fimbrial-like protein YehA"
FT /id="PRO_0000013867"
SQ SEQUENCE 344 AA; 36885 MW; CFC3A72B0227A033 CRC64;
MEIRIMLFIL MMMVMPVSYA ACYSELSVQH NLVVQGDFAL TQTQMATYEH NFNDSSCVST
NTITPMSPSD IIVGLYNDTI KLNLHFEWTN KNNITLSNNQ TSFTSGYSVT VTPAASNAKV
NVSAGGGGSV MINGVATLSS ASSSTRGSAA VQFLLCLLGG KSWDACVNSY RNALAQNAGV
YSFNLTLSYN PITTTCKPDD LLITLDSIPV SQLPATGNKA TINSKQGDII LRCKNLLGQQ
NQTSRKMQVY LSSSDLLTNS NTILKGAEDN GVGFILESNG SPVTLLNITN SSKGYTNLKE
VAAKSKLTDT TVSIPITASY YVYDTNKVKS GALEATALIN VKYD
