ID   YEJE_ECOLI              Reviewed;         341 AA.
AC   P33915;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   03-AUG-2022, entry version 151.
DE   RecName: Full=Inner membrane ABC transporter permease protein YejE;
GN   Name=yejE; OrderedLocusNames=b2179, JW2167;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / BHB2600;
RA   Richterich P., Lakey N., Gryan G., Jaehn L., Mintz L., Robison K.,
RA   Church G.M.;
RT   "Automated multiplex sequencing of the E.coli genome.";
RL   Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9097040; DOI=10.1093/dnares/3.6.379;
RA   Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K.,
RA   Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T.,
RA   Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S., Nakamura Y.,
RA   Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y.,
RA   Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y.,
RA   Horiuchi T.;
RT   "A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 40.1-50.0 min region on the linkage map.";
RL   DNA Res. 3:379-392(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   TOPOLOGY [LARGE SCALE ANALYSIS].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=15919996; DOI=10.1126/science.1109730;
RA   Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT   "Global topology analysis of the Escherichia coli inner membrane
RT   proteome.";
RL   Science 308:1321-1323(2005).
CC   -!- FUNCTION: Probably part of a binding-protein-dependent transport
CC       system. Probably responsible for the translocation of the substrate
CC       across the membrane.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. OppBC subfamily. {ECO:0000305}.
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DR   EMBL; U00008; AAA16378.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC75240.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA15987.1; -; Genomic_DNA.
DR   PIR; B64987; B64987.
DR   RefSeq; NP_416684.1; NC_000913.3.
DR   RefSeq; WP_000088923.1; NZ_LN832404.1.
DR   AlphaFoldDB; P33915; -.
DR   SMR; P33915; -.
DR   BioGRID; 4260475; 6.
DR   ComplexPortal; CPX-4362; Peptide ABC transporter complex.
DR   DIP; DIP-11935N; -.
DR   IntAct; P33915; 1.
DR   STRING; 511145.b2179; -.
DR   TCDB; 3.A.1.5.21; the atp-binding cassette (abc) superfamily.
DR   jPOST; P33915; -.
DR   PaxDb; P33915; -.
DR   PRIDE; P33915; -.
DR   EnsemblBacteria; AAC75240; AAC75240; b2179.
DR   EnsemblBacteria; BAA15987; BAA15987; BAA15987.
DR   GeneID; 946683; -.
DR   KEGG; ecj:JW2167; -.
DR   KEGG; eco:b2179; -.
DR   PATRIC; fig|1411691.4.peg.57; -.
DR   EchoBASE; EB1974; -.
DR   eggNOG; COG4239; Bacteria.
DR   HOGENOM; CLU_028518_4_1_6; -.
DR   InParanoid; P33915; -.
DR   OMA; PSPPTWM; -.
DR   PhylomeDB; P33915; -.
DR   BioCyc; EcoCyc:YEJE-MON; -.
DR   BioCyc; MetaCyc:YEJE-MON; -.
DR   PRO; PR:P33915; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0055052; C:ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; IC:ComplexPortal.
DR   GO; GO:0016020; C:membrane; IC:ComplexPortal.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR   GO; GO:0042884; P:microcin transport; IDA:ComplexPortal.
DR   GO; GO:0035672; P:oligopeptide transmembrane transport; IDA:EcoCyc.
DR   GO; GO:0015833; P:peptide transport; IC:ComplexPortal.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   InterPro; IPR025966; OppC_N.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   Pfam; PF12911; OppC_N; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..341
FT                   /note="Inner membrane ABC transporter permease protein
FT                   YejE"
FT                   /id="PRO_0000060259"
FT   TOPO_DOM        1..21
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TOPO_DOM        43..143
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        144..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TOPO_DOM        165..178
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        179..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TOPO_DOM        200..201
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        202..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TOPO_DOM        223..252
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        253..273
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TOPO_DOM        274..307
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        308..328
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TOPO_DOM        329..341
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          140..332
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   341 AA;  38092 MW;  3F86F7B0EF8E6C70 CRC64;
     MSRLSPVNQA RWARFRHNRR GYWSLWIFLV LFGLSLCSEL IANDKPLLVR YDGSWYFPLL
     KNYSESDFGG PLASQADYQD PWLKQRLENN GWVLWAPIRF GATSINFATN KPFPSPPSRQ
     NWLGTDANGG DVLARILYGT RISVLFGLML TLCSSVMGVL AGALQGYYGG KVDLWGQRFI
     EVWSGMPTLF LIILLSSVVQ PNFWWLLAIT VLFGWMSLVG VVRAEFLRTR NFDYIRAAQA
     LGVSDRSIIL RHMLPNAMVA TLTFLPFILC SSITTLTSLD FLGFGLPLGS PSLGELLLQG
     KNNLQAPWLG ITAFLSVAIL LSLLIFIGEA VRDAFDPNKA V