ID   YEJM_ECOL6              Reviewed;         586 AA.
AC   P0AD28; P33922; P33923;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Inner membrane protein YejM;
GN   Name=yejM; OrderedLocusNames=c2726;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: To H.influenzae HI_0842. {ECO:0000305}.
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DR   EMBL; AE014075; AAN81180.1; -; Genomic_DNA.
DR   RefSeq; WP_000256203.1; NC_004431.1.
DR   AlphaFoldDB; P0AD28; -.
DR   SMR; P0AD28; -.
DR   STRING; 199310.c2726; -.
DR   EnsemblBacteria; AAN81180; AAN81180; c2726.
DR   KEGG; ecc:c2726; -.
DR   eggNOG; COG3083; Bacteria.
DR   HOGENOM; CLU_030247_1_0_6; -.
DR   OMA; QMLFSRW; -.
DR   BioCyc; ECOL199310:C2726-MON; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008484; F:sulfuric ester hydrolase activity; IEA:InterPro.
DR   Gene3D; 3.40.720.10; -; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR000917; Sulfatase_N.
DR   InterPro; IPR012159; YejM.
DR   InterPro; IPR024588; YejM_N.
DR   Pfam; PF11893; DUF3413; 1.
DR   Pfam; PF00884; Sulfatase; 1.
DR   PIRSF; PIRSF004950; Mmb_sulf_HI0842; 1.
DR   SUPFAM; SSF53649; SSF53649; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..586
FT                   /note="Inner membrane protein YejM"
FT                   /id="PRO_0000169167"
FT   TOPO_DOM        1..20
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        21..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        44..57
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        58..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        81..84
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        85..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        104..134
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        158..168
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        169..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        192..586
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   586 AA;  67296 MW;  0460F8C00A0D5465 CRC64;
     MVTHRQRYRE KVSQMVSWGH WFALFNILLS LVIGSRYLFI ADWPTTLAGR IYSYVSIIGH
     FSFLVFATYL LILFPLTFIV GSQRLMRFLS VILATAGMTL LLIDSEVFTR FHLHLNPIVW
     QLVINPDENE MARDWQLMFI SVPVILLLEL VFATWSWQKL RSLTRRRRFA RPLAAFLFIA
     FIASHVVYIW ADANFYRPIT MQRANLPLSY PMTARRFLEK HGLLDAQEYQ RRLIEQGNPD
     AVSVQYPLSE LRYRDMGTGQ NVLLITVDGL NYSRFEKQMP ALAGFAEQNI SFTRHMSSGN
     TTDNGIFGLF YGISPSYMDG ILSTRTPAAL ITALNQQGYQ LGLFSSDGFT SPLYRQALLS
     DFSMPSVRTQ SDEQTATQWI NWLGRYAQED NRWFSWVSFN GTNIDDSNQQ AFARKYSRAA
     GNVDDQINRV LNALRDSGKL DNTVVIITAG RGIPLSEEEE TFDWSHGHLQ VPLVIHWPGT
     PAQRINALTD HTDLMTTLMQ RLLHVSTPAS EYSQGQDLFN PQRRHYWVTA ADNDTLAITT
     PKKTLVLNNN GKYRTYNLRG ERVKDEKPQL SLLLQVLTDE KRFIAN