YEJM_ECOLI
ID YEJM_ECOLI Reviewed; 586 AA.
AC P0AD27; P33922; P33923; Q2MAQ3;
DT 22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 22-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Inner membrane protein YejM;
GN Name=yejM; Synonyms=yejN; OrderedLocusNames=b2188, JW2176;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / BHB2600;
RA Richterich P., Lakey N., Gryan G., Jaehn L., Mintz L., Robison K.,
RA Church G.M.;
RT "Automated multiplex sequencing of the E.coli genome.";
RL Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP SEQUENCE REVISION.
RA Robison K.;
RL Submitted (FEB-1994) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: To H.influenzae HI_0842. {ECO:0000305}.
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DR EMBL; U00008; AAA16384.1; -; Genomic_DNA.
DR EMBL; U00096; AAC75249.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE76653.1; -; Genomic_DNA.
DR PIR; C64988; C64988.
DR RefSeq; NP_416693.1; NC_000913.3.
DR RefSeq; WP_000256203.1; NZ_STEB01000002.1.
DR PDB; 5I5H; X-ray; 1.65 A; A=1-586.
DR PDB; 6XLP; X-ray; 2.00 A; A=1-586.
DR PDBsum; 5I5H; -.
DR PDBsum; 6XLP; -.
DR AlphaFoldDB; P0AD27; -.
DR SMR; P0AD27; -.
DR BioGRID; 4260478; 16.
DR STRING; 511145.b2188; -.
DR TCDB; 2.A.127.1.2; the enterobacterial cardiolipin transporter (clt) family.
DR jPOST; P0AD27; -.
DR PaxDb; P0AD27; -.
DR PRIDE; P0AD27; -.
DR EnsemblBacteria; AAC75249; AAC75249; b2188.
DR EnsemblBacteria; BAE76653; BAE76653; BAE76653.
DR GeneID; 946685; -.
DR KEGG; ecj:JW2176; -.
DR KEGG; eco:b2188; -.
DR PATRIC; fig|1411691.4.peg.47; -.
DR EchoBASE; EB1981; -.
DR eggNOG; COG3083; Bacteria.
DR HOGENOM; CLU_030247_1_0_6; -.
DR InParanoid; P0AD27; -.
DR OMA; QMLFSRW; -.
DR PhylomeDB; P0AD27; -.
DR BioCyc; EcoCyc:EG12049-MON; -.
DR PRO; PR:P0AD27; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0008484; F:sulfuric ester hydrolase activity; IEA:InterPro.
DR DisProt; DP02484; -.
DR Gene3D; 3.40.720.10; -; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR000917; Sulfatase_N.
DR InterPro; IPR012159; YejM.
DR InterPro; IPR024588; YejM_N.
DR Pfam; PF11893; DUF3413; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR PIRSF; PIRSF004950; Mmb_sulf_HI0842; 1.
DR SUPFAM; SSF53649; SSF53649; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cell inner membrane; Cell membrane; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..586
FT /note="Inner membrane protein YejM"
FT /id="PRO_0000169165"
FT TOPO_DOM 1..20
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 21..43
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 44..57
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 58..80
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 81..84
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 85..103
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 104..134
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 135..157
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 158..168
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 169..191
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 192..586
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT HELIX 4..40
FT /evidence="ECO:0007829|PDB:6XLP"
FT HELIX 47..71
FT /evidence="ECO:0007829|PDB:6XLP"
FT HELIX 73..77
FT /evidence="ECO:0007829|PDB:6XLP"
FT HELIX 83..111
FT /evidence="ECO:0007829|PDB:6XLP"
FT HELIX 117..123
FT /evidence="ECO:0007829|PDB:6XLP"
FT HELIX 128..139
FT /evidence="ECO:0007829|PDB:6XLP"
FT HELIX 141..158
FT /evidence="ECO:0007829|PDB:6XLP"
FT HELIX 160..165
FT /evidence="ECO:0007829|PDB:6XLP"
FT HELIX 167..169
FT /evidence="ECO:0007829|PDB:6XLP"
FT HELIX 171..193
FT /evidence="ECO:0007829|PDB:6XLP"
FT HELIX 197..200
FT /evidence="ECO:0007829|PDB:6XLP"
FT TURN 201..204
FT /evidence="ECO:0007829|PDB:6XLP"
FT HELIX 215..220
FT /evidence="ECO:0007829|PDB:6XLP"
FT HELIX 226..236
FT /evidence="ECO:0007829|PDB:6XLP"
FT STRAND 247..249
FT /evidence="ECO:0007829|PDB:6XLP"
FT STRAND 253..256
FT /evidence="ECO:0007829|PDB:5I5H"
FT STRAND 262..270
FT /evidence="ECO:0007829|PDB:5I5H"
FT HELIX 275..278
FT /evidence="ECO:0007829|PDB:5I5H"
FT HELIX 280..287
FT /evidence="ECO:0007829|PDB:5I5H"
FT STRAND 289..296
FT /evidence="ECO:0007829|PDB:5I5H"
FT HELIX 302..311
FT /evidence="ECO:0007829|PDB:5I5H"
FT HELIX 315..317
FT /evidence="ECO:0007829|PDB:5I5H"
FT HELIX 318..323
FT /evidence="ECO:0007829|PDB:5I5H"
FT HELIX 329..336
FT /evidence="ECO:0007829|PDB:5I5H"
FT STRAND 340..347
FT /evidence="ECO:0007829|PDB:5I5H"
FT HELIX 348..350
FT /evidence="ECO:0007829|PDB:6XLP"
FT HELIX 352..356
FT /evidence="ECO:0007829|PDB:5I5H"
FT HELIX 358..361
FT /evidence="ECO:0007829|PDB:5I5H"
FT STRAND 366..368
FT /evidence="ECO:0007829|PDB:5I5H"
FT HELIX 372..385
FT /evidence="ECO:0007829|PDB:5I5H"
FT HELIX 387..389
FT /evidence="ECO:0007829|PDB:5I5H"
FT STRAND 391..399
FT /evidence="ECO:0007829|PDB:5I5H"
FT HELIX 409..436
FT /evidence="ECO:0007829|PDB:5I5H"
FT HELIX 440..442
FT /evidence="ECO:0007829|PDB:6XLP"
FT STRAND 443..452
FT /evidence="ECO:0007829|PDB:5I5H"
FT HELIX 457..460
FT /evidence="ECO:0007829|PDB:5I5H"
FT HELIX 466..469
FT /evidence="ECO:0007829|PDB:5I5H"
FT STRAND 473..476
FT /evidence="ECO:0007829|PDB:5I5H"
FT STRAND 483..485
FT /evidence="ECO:0007829|PDB:5I5H"
FT HELIX 491..501
FT /evidence="ECO:0007829|PDB:5I5H"
FT HELIX 509..511
FT /evidence="ECO:0007829|PDB:5I5H"
FT STRAND 528..531
FT /evidence="ECO:0007829|PDB:5I5H"
FT STRAND 533..539
FT /evidence="ECO:0007829|PDB:5I5H"
FT STRAND 541..548
FT /evidence="ECO:0007829|PDB:5I5H"
FT STRAND 553..557
FT /evidence="ECO:0007829|PDB:5I5H"
FT HELIX 570..579
FT /evidence="ECO:0007829|PDB:6XLP"
FT TURN 580..583
FT /evidence="ECO:0007829|PDB:6XLP"
SQ SEQUENCE 586 AA; 67296 MW; 0460F8C00A0D5465 CRC64;
MVTHRQRYRE KVSQMVSWGH WFALFNILLS LVIGSRYLFI ADWPTTLAGR IYSYVSIIGH
FSFLVFATYL LILFPLTFIV GSQRLMRFLS VILATAGMTL LLIDSEVFTR FHLHLNPIVW
QLVINPDENE MARDWQLMFI SVPVILLLEL VFATWSWQKL RSLTRRRRFA RPLAAFLFIA
FIASHVVYIW ADANFYRPIT MQRANLPLSY PMTARRFLEK HGLLDAQEYQ RRLIEQGNPD
AVSVQYPLSE LRYRDMGTGQ NVLLITVDGL NYSRFEKQMP ALAGFAEQNI SFTRHMSSGN
TTDNGIFGLF YGISPSYMDG ILSTRTPAAL ITALNQQGYQ LGLFSSDGFT SPLYRQALLS
DFSMPSVRTQ SDEQTATQWI NWLGRYAQED NRWFSWVSFN GTNIDDSNQQ AFARKYSRAA
GNVDDQINRV LNALRDSGKL DNTVVIITAG RGIPLSEEEE TFDWSHGHLQ VPLVIHWPGT
PAQRINALTD HTDLMTTLMQ RLLHVSTPAS EYSQGQDLFN PQRRHYWVTA ADNDTLAITT
PKKTLVLNNN GKYRTYNLRG ERVKDEKPQL SLLLQVLTDE KRFIAN
