ID   YEJM_SALTI              Reviewed;         586 AA.
AC   Q8Z579;
DT   23-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=Inner membrane protein YejM;
GN   Name=yejM; OrderedLocusNames=STY2466, t0626;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: To H.influenzae HI_0842. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL513382; CAD02611.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO68327.1; -; Genomic_DNA.
DR   RefSeq; NP_456786.1; NC_003198.1.
DR   AlphaFoldDB; Q8Z579; -.
DR   SMR; Q8Z579; -.
DR   STRING; 220341.16503467; -.
DR   EnsemblBacteria; AAO68327; AAO68327; t0626.
DR   KEGG; stt:t0626; -.
DR   KEGG; sty:STY2466; -.
DR   PATRIC; fig|220341.7.peg.2493; -.
DR   eggNOG; COG3083; Bacteria.
DR   HOGENOM; CLU_030247_1_0_6; -.
DR   OMA; QMLFSRW; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008484; F:sulfuric ester hydrolase activity; IEA:InterPro.
DR   Gene3D; 3.40.720.10; -; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR000917; Sulfatase_N.
DR   InterPro; IPR012159; YejM.
DR   InterPro; IPR024588; YejM_N.
DR   Pfam; PF11893; DUF3413; 1.
DR   Pfam; PF00884; Sulfatase; 1.
DR   PIRSF; PIRSF004950; Mmb_sulf_HI0842; 1.
DR   SUPFAM; SSF53649; SSF53649; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..586
FT                   /note="Inner membrane protein YejM"
FT                   /id="PRO_0000169168"
FT   TOPO_DOM        1..20
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        21..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        44..57
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        58..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        81..84
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        85..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        104..134
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        158..168
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        169..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        192..586
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        400
FT                   /note="S -> N (in Ref. 2; AAO68327)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   586 AA;  67105 MW;  322223AC20E76A96 CRC64;
     MVTHRQRYRE KVSQMVSWGH WFALFNILLA TLLGSRYLFV ADWPTTLAGR IYSYLSIVGH
     FSFLVFATYL LILFPLTFIV MSQRLMRFLS AILATAGMTL LLIDSEVFTR FHLHLNPIVW
     ELVINPDQNE MARDWQLMFI SVPVILLIEM LFATWSWQKL RSLTRRRHFA RPLAAFFFVS
     FIASHLIYIW ADANFYRPIT MQRANLPLSY PMTARRFLEK HGLLDAQEYQ RRLVEQGNPE
     AVSVQYPLSN LHYRDMGTGQ NVLLITVDGL NYSRFEKQMP ELATFAEQNI DFTRHMSSGN
     TTDNGIFGLF YGISPGYMDG VLSTRTPAAL ITALNQQGYQ LGLFSSDGFA SPLYRQALLS
     DFSMPAAQTQ SDAQTASQWI DWLGRYAQED NRWFSWISFS GTNIDDSNQK NFVKRYASAA
     SDVDAQINRV LNALREAGKF DNTVVIITAG RGIPLTPEEN RFDWSQGHLQ VPLVIHWPGT
     PAQRINVLTD HTDVMTTLMQ RLLHVSTPAN EYSQGQDIFT VPRRHNWVTA ADGSTLAITT
     PQMTLVLNNN GHYQTYDLHG EKIKDQKPQL SLLLQVLTEE KRFIAN