YEJM_SALTY
ID YEJM_SALTY Reviewed; 586 AA.
AC P40709;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 13-DEC-2001, sequence version 2.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Inner membrane protein YejM;
GN Name=yejM; OrderedLocusNames=STM2228;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 397-586.
RX PubMed=1630916; DOI=10.1093/nar/20.13.3463;
RA Sroga G.E., Nemoto F., Kuchino Y., Bjoerk G.R.;
RT "Insertion (sufB) in the anticodon loop or base substitution (sufC) in the
RT anticodon stem of tRNA(Pro)2 from Salmonella typhimurium induces
RT suppression of frameshift mutations.";
RL Nucleic Acids Res. 20:3463-3469(1992).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: To H.influenzae HI_0842. {ECO:0000305}.
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DR EMBL; AE006468; AAL21131.1; -; Genomic_DNA.
DR EMBL; X63777; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_461172.1; NC_003197.2.
DR RefSeq; WP_000256150.1; NC_003197.2.
DR PDB; 5I5D; X-ray; 1.64 A; A/B/C/D=1-586.
DR PDB; 5I5F; X-ray; 1.84 A; A/B/C/D=1-586.
DR PDB; 6V8Q; X-ray; 2.70 A; A/B=1-586.
DR PDB; 6VAT; X-ray; 2.35 A; A/B/C/D/E/F=241-586.
DR PDB; 6VC7; X-ray; 2.05 A; A/B/C/D/E/F=241-586.
DR PDB; 6VDF; X-ray; 1.92 A; A/B/C/D=241-586.
DR PDBsum; 5I5D; -.
DR PDBsum; 5I5F; -.
DR PDBsum; 6V8Q; -.
DR PDBsum; 6VAT; -.
DR PDBsum; 6VC7; -.
DR PDBsum; 6VDF; -.
DR AlphaFoldDB; P40709; -.
DR SMR; P40709; -.
DR STRING; 99287.STM2228; -.
DR PaxDb; P40709; -.
DR EnsemblBacteria; AAL21131; AAL21131; STM2228.
DR GeneID; 1253750; -.
DR KEGG; stm:STM2228; -.
DR PATRIC; fig|99287.12.peg.2360; -.
DR HOGENOM; CLU_030247_1_0_6; -.
DR OMA; QMLFSRW; -.
DR PhylomeDB; P40709; -.
DR BioCyc; SENT99287:STM2228-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0008484; F:sulfuric ester hydrolase activity; IEA:InterPro.
DR DisProt; DP02485; -.
DR Gene3D; 3.40.720.10; -; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR000917; Sulfatase_N.
DR InterPro; IPR012159; YejM.
DR InterPro; IPR024588; YejM_N.
DR Pfam; PF11893; DUF3413; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR PIRSF; PIRSF004950; Mmb_sulf_HI0842; 1.
DR SUPFAM; SSF53649; SSF53649; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cell inner membrane; Cell membrane; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..586
FT /note="Inner membrane protein YejM"
FT /id="PRO_0000169169"
FT TOPO_DOM 1..20
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 21..43
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 44..57
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 58..80
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 81..84
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 85..103
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 104..134
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 135..157
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 158..168
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 169..191
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 192..586
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT HELIX 9..33
FT /evidence="ECO:0007829|PDB:6V8Q"
FT HELIX 35..40
FT /evidence="ECO:0007829|PDB:6V8Q"
FT HELIX 49..71
FT /evidence="ECO:0007829|PDB:6V8Q"
FT HELIX 73..79
FT /evidence="ECO:0007829|PDB:6V8Q"
FT HELIX 83..111
FT /evidence="ECO:0007829|PDB:6V8Q"
FT HELIX 117..124
FT /evidence="ECO:0007829|PDB:6V8Q"
FT HELIX 133..158
FT /evidence="ECO:0007829|PDB:6V8Q"
FT TURN 159..161
FT /evidence="ECO:0007829|PDB:6V8Q"
FT HELIX 171..193
FT /evidence="ECO:0007829|PDB:6V8Q"
FT HELIX 197..200
FT /evidence="ECO:0007829|PDB:6V8Q"
FT TURN 201..205
FT /evidence="ECO:0007829|PDB:6V8Q"
FT HELIX 215..220
FT /evidence="ECO:0007829|PDB:6V8Q"
FT HELIX 228..236
FT /evidence="ECO:0007829|PDB:6V8Q"
FT STRAND 247..249
FT /evidence="ECO:0007829|PDB:5I5D"
FT STRAND 253..256
FT /evidence="ECO:0007829|PDB:5I5D"
FT STRAND 261..270
FT /evidence="ECO:0007829|PDB:5I5D"
FT HELIX 275..278
FT /evidence="ECO:0007829|PDB:5I5D"
FT HELIX 280..287
FT /evidence="ECO:0007829|PDB:5I5D"
FT STRAND 289..296
FT /evidence="ECO:0007829|PDB:5I5D"
FT HELIX 302..311
FT /evidence="ECO:0007829|PDB:5I5D"
FT HELIX 315..317
FT /evidence="ECO:0007829|PDB:5I5D"
FT HELIX 318..324
FT /evidence="ECO:0007829|PDB:5I5D"
FT HELIX 329..336
FT /evidence="ECO:0007829|PDB:5I5D"
FT STRAND 340..345
FT /evidence="ECO:0007829|PDB:5I5D"
FT HELIX 352..356
FT /evidence="ECO:0007829|PDB:5I5D"
FT TURN 357..361
FT /evidence="ECO:0007829|PDB:5I5D"
FT HELIX 372..385
FT /evidence="ECO:0007829|PDB:5I5D"
FT STRAND 389..391
FT /evidence="ECO:0007829|PDB:6VDF"
FT STRAND 393..399
FT /evidence="ECO:0007829|PDB:5I5D"
FT TURN 407..410
FT /evidence="ECO:0007829|PDB:5I5D"
FT HELIX 412..436
FT /evidence="ECO:0007829|PDB:5I5D"
FT HELIX 440..442
FT /evidence="ECO:0007829|PDB:5I5D"
FT STRAND 443..452
FT /evidence="ECO:0007829|PDB:5I5D"
FT HELIX 457..460
FT /evidence="ECO:0007829|PDB:5I5D"
FT HELIX 466..469
FT /evidence="ECO:0007829|PDB:5I5D"
FT STRAND 473..476
FT /evidence="ECO:0007829|PDB:5I5D"
FT STRAND 483..485
FT /evidence="ECO:0007829|PDB:5I5D"
FT HELIX 491..501
FT /evidence="ECO:0007829|PDB:5I5D"
FT HELIX 509..511
FT /evidence="ECO:0007829|PDB:5I5D"
FT STRAND 520..522
FT /evidence="ECO:0007829|PDB:6V8Q"
FT STRAND 528..531
FT /evidence="ECO:0007829|PDB:5I5D"
FT STRAND 533..539
FT /evidence="ECO:0007829|PDB:5I5D"
FT STRAND 544..548
FT /evidence="ECO:0007829|PDB:5I5D"
FT STRAND 553..556
FT /evidence="ECO:0007829|PDB:5I5D"
FT HELIX 570..580
FT /evidence="ECO:0007829|PDB:5I5D"
FT HELIX 581..583
FT /evidence="ECO:0007829|PDB:5I5D"
SQ SEQUENCE 586 AA; 67132 MW; 3233DF412C06967B CRC64;
MVTHRQRYRE KVSQMVSWGH WFALFNILLA TLLGSRYLFV ADWPTTLAGR IYSYLSIVGH
FSFLVFATYL LILFPLTFIV MSQRLMRFLS AILATAGMTL LLIDSEVFTR FHLHLNPIVW
ELVINPDQNE MARDWQLMFI SVPVILLIEM LFATWSWQKL RSLTRRRHFA RPLAAFFFVS
FIASHLIYIW ADANFYRPIT MQRANLPLSY PMTARRFLEK HGLLDAQEYQ RRLVEQGNPE
AVSVQYPLSN LHYRDMGTGQ NVLLITVDGL NYSRFEKQMP ELATFAEQNI DFTRHMSSGN
TTDNGIFGLF YGISPGYMDG VLSTRTPAAL ITALNQQGYQ LGLFSSDGFA SPLYRQALLS
DFSMPAAQTQ SDAQTASQWI DWLGRYAQED NRWFSWISFN GTNIDDSNQK NFVKRYASAA
SDVDAQINRV LNALREAGKF DNTVVIITAG RGIPLTPEEN RFDWSQGHLQ VPLVIHWPGT
PAQRINVLTD HTDVMTTLMQ RLLHVSTPAN EYSQGQDIFT VPRRHNWVTA ADGSTLAITT
PQMTLVLNNN GHYQTYDLHG EKIKDQKPQL SLLLQVLTEE KRFIAN
