YEKI_SCHPO
ID YEKI_SCHPO Reviewed; 391 AA.
AC O36030;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 25-MAY-2022, entry version 136.
DE RecName: Full=Uncharacterized WD repeat-containing protein C4F10.18;
GN ORFNames=SPAC4F10.18;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- INTERACTION:
CC O36030; O43044: nup120; NbExp=3; IntAct=EBI-16014622, EBI-1563733;
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000269|PubMed:16823372}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CU329670; CAB11721.1; -; Genomic_DNA.
DR PIR; T38822; T38822.
DR RefSeq; NP_594761.1; NM_001020188.2.
DR PDB; 4FHL; X-ray; 2.60 A; A=1-391.
DR PDB; 4FHM; X-ray; 4.34 A; A=1-391.
DR PDB; 4FHN; X-ray; 6.99 A; A/C=1-391.
DR PDB; 4GQ1; X-ray; 2.40 A; A=1-391.
DR PDB; 4GQ2; X-ray; 2.40 A; P=1-391.
DR PDBsum; 4FHL; -.
DR PDBsum; 4FHM; -.
DR PDBsum; 4FHN; -.
DR PDBsum; 4GQ1; -.
DR PDBsum; 4GQ2; -.
DR AlphaFoldDB; O36030; -.
DR SMR; O36030; -.
DR BioGRID; 280007; 36.
DR DIP; DIP-60077N; -.
DR IntAct; O36030; 1.
DR STRING; 4896.SPAC4F10.18.1; -.
DR MaxQB; O36030; -.
DR PaxDb; O36030; -.
DR EnsemblFungi; SPAC4F10.18.1; SPAC4F10.18.1:pep; SPAC4F10.18.
DR GeneID; 2543592; -.
DR KEGG; spo:SPAC4F10.18; -.
DR PomBase; SPAC4F10.18; -.
DR VEuPathDB; FungiDB:SPAC4F10.18; -.
DR eggNOG; ENOG502SF1P; Eukaryota.
DR HOGENOM; CLU_679999_0_0_1; -.
DR InParanoid; O36030; -.
DR OMA; IGHDTGI; -.
DR Reactome; R-SPO-159227; Transport of the SLBP independent Mature mRNA.
DR Reactome; R-SPO-159231; Transport of Mature mRNA Derived from an Intronless Transcript.
DR Reactome; R-SPO-159236; Transport of Mature mRNA derived from an Intron-Containing Transcript.
DR Reactome; R-SPO-3232142; SUMOylation of ubiquitinylation proteins.
DR Reactome; R-SPO-4085377; SUMOylation of SUMOylation proteins.
DR Reactome; R-SPO-4551638; SUMOylation of chromatin organization proteins.
DR Reactome; R-SPO-4570464; SUMOylation of RNA binding proteins.
DR Reactome; R-SPO-5578749; Transcriptional regulation by small RNAs.
DR Reactome; R-SPO-9615933; Postmitotic nuclear pore complex (NPC) reformation.
DR PRO; PR:O36030; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005643; C:nuclear pore; IDA:PomBase.
DR GO; GO:0031080; C:nuclear pore outer ring; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0006913; P:nucleocytoplasmic transport; IC:PomBase.
DR Gene3D; 2.130.10.10; -; 1.
DR InterPro; IPR037626; NUP37.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR22806; PTHR22806; 1.
DR Pfam; PF00400; WD40; 1.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF50978; SSF50978; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cytoplasm; Nucleus; Reference proteome; Repeat; WD repeat.
FT CHAIN 1..391
FT /note="Uncharacterized WD repeat-containing protein
FT C4F10.18"
FT /id="PRO_0000316556"
FT REPEAT 137..179
FT /note="WD 1"
FT REPEAT 182..222
FT /note="WD 2"
FT STRAND 3..9
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 16..21
FT /evidence="ECO:0007829|PDB:4GQ1"
FT HELIX 26..28
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 31..47
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 50..52
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 55..65
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 70..75
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 80..82
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 97..106
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 111..117
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 120..127
FT /evidence="ECO:0007829|PDB:4GQ1"
FT TURN 129..131
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 137..146
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 148..150
FT /evidence="ECO:0007829|PDB:4GQ2"
FT STRAND 151..161
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 164..172
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 175..182
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 187..193
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 196..204
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 207..213
FT /evidence="ECO:0007829|PDB:4GQ1"
FT TURN 214..217
FT /evidence="ECO:0007829|PDB:4GQ2"
FT HELIX 218..222
FT /evidence="ECO:0007829|PDB:4GQ2"
FT STRAND 234..239
FT /evidence="ECO:0007829|PDB:4GQ1"
FT HELIX 240..242
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 252..254
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 256..261
FT /evidence="ECO:0007829|PDB:4GQ1"
FT TURN 262..265
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 267..271
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 275..281
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 285..288
FT /evidence="ECO:0007829|PDB:4GQ2"
FT HELIX 293..298
FT /evidence="ECO:0007829|PDB:4GQ2"
FT STRAND 306..310
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 319..321
FT /evidence="ECO:0007829|PDB:4FHL"
FT STRAND 328..333
FT /evidence="ECO:0007829|PDB:4GQ1"
FT TURN 334..337
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 338..343
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 351..355
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 360..365
FT /evidence="ECO:0007829|PDB:4GQ1"
FT STRAND 369..385
FT /evidence="ECO:0007829|PDB:4GQ1"
FT HELIX 386..388
FT /evidence="ECO:0007829|PDB:4GQ1"
SQ SEQUENCE 391 AA; 42776 MW; 378B5289C494AB3D CRC64;
MTLSSNQYQL PLNVRPYTTT WCSQSPSCSN LLAIGHDTGI TIYCASEEQT PGSTGLTLQE
LFTIQTGLPT LHLSFSSSCS YSENLHDGDG NVNSSPVYSL FLACVCQDNT VRLIITKNET
IITQHVLGGK SGHHNFVNDI DIADVYSADN RLAEQVIASV GDDCTLIIWR LTDEGPILAG
YPLSSPGISV QFRPSNPNQL IVGERNGNIR IFDWTLNLSA EENSQTELVK NPWLLTLNTL
PLVNTCHSSG IASSLANVRW IGSDGSGILA MCKSGAWLRW NLFANNDYNE ISDSTMKLGP
KNLLPNVQGI SLFPSLLGAC PHPRYMDYFA TAHSQHGLIQ LINTYEKDSN SIPIQLGMPI
VDFCWHQDGS HLAIATEGSV LLTRLMGFTR L
