YELD_SCHPO
ID YELD_SCHPO Reviewed; 778 AA.
AC O14244;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 25-MAY-2022, entry version 100.
DE RecName: Full=Uncharacterized membrane protein C6F6.13c;
GN ORFNames=SPAC6F6.13c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the TMCO4 family. {ECO:0000305}.
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DR EMBL; CU329670; CAB11736.1; -; Genomic_DNA.
DR PIR; T39047; T39047.
DR RefSeq; NP_593906.1; NM_001019336.2.
DR AlphaFoldDB; O14244; -.
DR BioGRID; 278596; 3.
DR STRING; 4896.SPAC6F6.13c.1; -.
DR ESTHER; schpo-yeld; Duf_726.
DR MaxQB; O14244; -.
DR PaxDb; O14244; -.
DR PRIDE; O14244; -.
DR EnsemblFungi; SPAC6F6.13c.1; SPAC6F6.13c.1:pep; SPAC6F6.13c.
DR GeneID; 2542120; -.
DR KEGG; spo:SPAC6F6.13c; -.
DR PomBase; SPAC6F6.13c; -.
DR VEuPathDB; FungiDB:SPAC6F6.13c; -.
DR eggNOG; KOG2385; Eukaryota.
DR HOGENOM; CLU_001695_2_0_1; -.
DR InParanoid; O14244; -.
DR OMA; GHLAYRE; -.
DR PhylomeDB; O14244; -.
DR PRO; PR:O14244; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR GO; GO:0005794; C:Golgi apparatus; HDA:PomBase.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; ISM:PomBase.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR007941; DUF726.
DR PANTHER; PTHR17920; PTHR17920; 2.
DR Pfam; PF05277; DUF726; 1.
DR SUPFAM; SSF53474; SSF53474; 1.
PE 3: Inferred from homology;
KW Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..778
FT /note="Uncharacterized membrane protein C6F6.13c"
FT /id="PRO_0000340087"
FT TRANSMEM 356..381
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 401..423
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 778 AA; 86129 MW; 0B0B2AC38E5D1796 CRC64;
MPISSPGTRC SSDLKDPTLQ QYSAESVSTE QSLGTFEESK GSITENYVQD SSVDEHDDGN
WQPMEVISLE PTHLINDIDD DNEIIEEKKE TEKVEESELE PRYTRVFRDE DDDQKHQLDS
EAIKLLDIAD HGNEEISMDS QLEITGNILS ETEKMAYAGV CRLLILKMVD KIACFTTLPW
YRGECKAALE DTIMWADKTT SCIYEHLGVT VEEQKMIENL HKHSVQIDDL SKILVSAHRA
QTVSSLDAVL VDEVESSDSL SSLGKEKPVQ IDVRWTVLCD LFLVLISKSL YDCRSRSLLM
AVGEVLDINE FDVAKFEKHI VETIQIDDTG ELEAGSSANT EAVMKLRRKV SRRKKYILMG
LAGIGGGLVI GLSSGLLAPI ISAGIGAAFT TVGLSGVATS GFLAGGGSAA LITAGGAISG
AHIGTTGMAH RKADVKTFEF RPLHAQRRAN VIVTVSGWML SKEDDVRLSF ATLDPIVGDI
YSVFWEPEML ASAGQTMNIL ATEVVTQSLQ QVLGSTVLVS LMGALQWPLI LTKLGYLIDN
PWNNSLDRAK ATGQLLADML CYRSLGVRPV TLVGYSLGAR VIYYCLRELE KKKEFSIIEN
VYLFGTPVIF KRTSWLKAAS VVSGRFVNGY KKNDWILGYL FRATSGGIGR VAGLRQIDCI
PGIENIDVTN LVSGHLAYRE SMPILLAAVG FEVLDEEVDL VSEPIPEPLR ERQSQLLYEI
EAEECQNKQK ELIEKSLMQK GRSLSPKKSN AFFDSKKIRE ELKKVKKKYG SSFNSRWY
