ID   YELL_DROER              Reviewed;         541 AA.
AC   Q9BI23;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Protein yellow;
DE   Flags: Precursor;
GN   Name=y;
OS   Drosophila erecta (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7220;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=11371593; DOI=10.1093/oxfordjournals.molbev.a003876;
RA   Munte A.B., Aguade M., Segarra C.;
RT   "Changes in the recombinational environment affect divergence in the yellow
RT   gene of Drosophila.";
RL   Mol. Biol. Evol. 18:1045-1056(2001).
CC   -!- FUNCTION: Controls the pigmentation pattern of the adult cuticle and
CC       larval mouth parts. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the major royal jelly protein family.
CC       {ECO:0000305}.
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DR   EMBL; AJ300670; CAC34735.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9BI23; -.
DR   SMR; Q9BI23; -.
DR   STRING; 7220.FBpp0131326; -.
DR   eggNOG; ENOG502QQ50; Eukaryota.
DR   GO; GO:0070451; C:cell hair; IEA:EnsemblMetazoa.
DR   GO; GO:0005737; C:cytoplasm; IEA:EnsemblMetazoa.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0048067; P:cuticle pigmentation; IEA:EnsemblMetazoa.
DR   GO; GO:0048065; P:male courtship behavior, veined wing extension; IEA:EnsemblMetazoa.
DR   GO; GO:0042438; P:melanin biosynthetic process; IEA:EnsemblMetazoa.
DR   GO; GO:0048082; P:regulation of adult chitin-containing cuticle pigmentation; IEA:EnsemblMetazoa.
DR   Gene3D; 2.120.10.30; -; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR017996; Royal_jelly/protein_yellow.
DR   InterPro; IPR029846; Yellow.
DR   PANTHER; PTHR10009; PTHR10009; 1.
DR   PANTHER; PTHR10009:SF14; PTHR10009:SF14; 1.
DR   Pfam; PF03022; MRJP; 1.
DR   PRINTS; PR01366; ROYALJELLY.
PE   3: Inferred from homology;
KW   Developmental protein; Glycoprotein; Secreted; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..541
FT                   /note="Protein yellow"
FT                   /id="PRO_0000031048"
FT   CARBOHYD        144
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   541 AA;  60550 MW;  1B87DBA834C1780D CRC64;
     MFQDKGWVLV TLIALVTPSW AAYKLQERYS WNQLDFAFPN ARLKEQALAS GDYIPQNALP
     VGVEHFGNRL FVTVPRWRDG IPATLTYINM DRSLTGSPEL IPYPDWRSNT AGDCANSITT
     AYRIKVDECG RLWVLDTGTV GIGNTTTNPC PYAVNVYDLT TDTRIRRYVL PAVDTNPNTF
     IANIAVDIGK NCDDAYAYFA DELGYGLIAY SWEQDKSWRF SAHSYFFPDP LRGDFNVAGI
     NFQWGEEGIF GMSLSPIRSD GYRTLYFSPL ASHRQFAVST RILRDETRTE DSYHDFVALD
     ERGPNSHTTS RVMSDDGIEL FNLIDQNAVG CWHSSMPYSP QFHGIVDRDD VGLVFPADVK
     IDENKNVWVL SDRMPVFLLS DLDYSDTNFR IYTAPLATLI ENTVCDLRNN AYGPPNTVSI
     PKQAVLPVGP PLYTKQYRPV LPQKPQTSWA SSPPPPSRTY LPANSGNVVS SISVSTNTVG
     PAGVEVPKAY IFNQHNGINY ETSGPHLFPT LQPAQSGRQD GGLKTYVNAR QSGWWHHQHQ
     G