ID   YELL_DROSI              Reviewed;         541 AA.
AC   P62407; Q9BH20;
DT   05-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Protein yellow;
DE   Flags: Precursor;
GN   Name=y;
OS   Drosophila simulans (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7240;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=11371593; DOI=10.1093/oxfordjournals.molbev.a003876;
RA   Munte A.B., Aguade M., Segarra C.;
RT   "Changes in the recombinational environment affect divergence in the yellow
RT   gene of Drosophila.";
RL   Mol. Biol. Evol. 18:1045-1056(2001).
CC   -!- FUNCTION: Controls the pigmentation pattern of the adult cuticle and
CC       larval mouth parts. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the major royal jelly protein family.
CC       {ECO:0000305}.
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DR   EMBL; AJ300668; CAC34738.1; -; Genomic_DNA.
DR   RefSeq; XP_016037524.1; XM_016180986.1.
DR   AlphaFoldDB; P62407; -.
DR   SMR; P62407; -.
DR   EnsemblMetazoa; FBtr0358744; FBpp0322723; FBgn0012903.
DR   GeneID; 6739897; -.
DR   Bgee; FBgn0012903; Expressed in embryo and 2 other tissues.
DR   GO; GO:0070451; C:cell hair; IEA:EnsemblMetazoa.
DR   GO; GO:0005737; C:cytoplasm; IEA:EnsemblMetazoa.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0048067; P:cuticle pigmentation; IEA:EnsemblMetazoa.
DR   GO; GO:0048065; P:male courtship behavior, veined wing extension; IEA:EnsemblMetazoa.
DR   GO; GO:0042438; P:melanin biosynthetic process; IEA:EnsemblMetazoa.
DR   GO; GO:0048082; P:regulation of adult chitin-containing cuticle pigmentation; IEA:EnsemblMetazoa.
DR   Gene3D; 2.120.10.30; -; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR017996; Royal_jelly/protein_yellow.
DR   InterPro; IPR029846; Yellow.
DR   PANTHER; PTHR10009; PTHR10009; 1.
DR   PANTHER; PTHR10009:SF14; PTHR10009:SF14; 1.
DR   Pfam; PF03022; MRJP; 1.
DR   PRINTS; PR01366; ROYALJELLY.
PE   3: Inferred from homology;
KW   Glycoprotein; Secreted; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..541
FT                   /note="Protein yellow"
FT                   /id="PRO_0000031054"
FT   REGION          443..463
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        144
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        215
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   541 AA;  60603 MW;  DADA1EDB485F9B6F CRC64;
     MFQDKGWILV TLITLVTPSW AAYKLQERYS WNQLDFAFPN TRLKDQALAS GDYIPQNALP
     VGVEHFGNRL FVTVPRWRDG IPATLTYINM DRSLTGSPEL IPYPDWRSNT AGDCANSITT
     AYRIKVDECG RLWVLDTGTV GIGNTTTNPC PYAVNVFDLT TDTRIRRYEL PGVDTNPNTF
     IANIAVDIGK NCDDAYAYFA DELGYGLIAY SWELNKSWRF SAHSYFFPDP LRGDFNVAGI
     NFQWGEEGIF GMSLSPIRSD GYRTLYFSPL ASHRQFAVST RILRDETRTE DSYHDFVALD
     ERGPNSHTTS RVMSDDGIEL FNLIDQNAVG CWHSSMPYSP QFHGIVDRDD VGLVFPADVK
     IDENKNVWVL SDRMPVFLLS DLDYSDTNFR IYTAPLATLI ENTVCDLRNN AYGPPNTVSI
     PKQAVLPMGP PLYTKQYRPL LPQKPQTSWA SSPPPPSRTY LPANSGNVVS SISVSTNSVG
     PAGVEVPKAY IFNQHNGINY ETSGPHLFPT HQPAQPGVQD GGLKTYVNAR QSGWWHHQHQ
     G