ID   YENR_YEREN              Reviewed;         244 AA.
AC   P54295;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Transcriptional activator protein YenR;
GN   Name=yenR;
OS   Yersinia enterocolitica.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=630;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=NCTC 10460;
RX   PubMed=7494483; DOI=10.1111/j.1365-2958.1995.mmi_17020345.x;
RA   Throup J.P., Camara M., Briggs G.S., Winson M.K., Chhabra S.R.,
RA   Bycroft B.W., Williams P., Stewart G.S.A.B.;
RT   "Characterisation of the yenI/yenR locus from Yersinia enterocolitica
RT   mediating the synthesis of two N-acylhomoserine lactone signal molecules.";
RL   Mol. Microbiol. 17:345-356(1995).
CC   -!- FUNCTION: Probable transcriptional activator. Binds to autoinducer
CC       molecules OHHL and HHL.
CC   -!- SIMILARITY: Belongs to the autoinducer-regulated transcriptional
CC       regulatory protein family. {ECO:0000305}.
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DR   EMBL; X76082; CAA53694.1; -; Genomic_DNA.
DR   PIR; S70176; S70176.
DR   RefSeq; WP_005160131.1; NZ_UHIX01000001.1.
DR   AlphaFoldDB; P54295; -.
DR   SMR; P54295; -.
DR   STRING; 1443113.LC20_03388; -.
DR   eggNOG; COG2771; Bacteria.
DR   OMA; NFHIRSV; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009372; P:quorum sensing; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.30.450.80; -; 1.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR005143; TF_LuxR_autoind-bd_dom.
DR   InterPro; IPR036693; TF_LuxR_autoind-bd_dom_sf.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF03472; Autoind_bind; 1.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   SUPFAM; SSF75516; SSF75516; 1.
DR   PROSITE; PS00622; HTH_LUXR_1; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Quorum sensing; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..244
FT                   /note="Transcriptional activator protein YenR"
FT                   /id="PRO_0000184196"
FT   DOMAIN          174..239
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT   DNA_BIND        198..217
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
SQ   SEQUENCE   244 AA;  28248 MW;  4F0318F3128AAEC5 CRC64;
     MIIDYFDNES INEDIKNYIQ RRIKTYGDLC YSYLVMNKKT PLHPTIISNY PLDWVKKYKK
     NSYHLIDPVI LTAKDKVAPF AWDDNSVINK KSTDSAVFKL AREYNIVNGY TFVLHDNSNN
     MATLNISNGS DDSISFDERI EINKEKIQML LIITHEKMLG LYQSNSDKNE NRNTQIERDI
     FSPRENEILY WASVGKTYAE ISIILGIKRS TVKFHIGNVV RKLGVLNAKH AIRLGIELKL
     IKPI