YEOB_SCHPO
ID YEOB_SCHPO Reviewed; 636 AA.
AC O13789;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Uncharacterized beta-glucan synthesis-associated protein C17G6.11c;
GN ORFNames=SPAC17G6.11c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1] {ECO:0000312|EMBL:CAB16222.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2] {ECO:0000305}
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- FUNCTION: Required for synthesis of the major beta-glucans of the yeast
CC cell wall. {ECO:0000250|UniProtKB:P33336}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000269|PubMed:16823372}; Single-pass type II membrane protein
CC {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the SKN1/KRE6 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CU329670; CAB16222.1; -; Genomic_DNA.
DR PIR; T37843; T37843.
DR RefSeq; NP_594258.1; NM_001019681.2.
DR AlphaFoldDB; O13789; -.
DR BioGRID; 278646; 1.
DR STRING; 4896.SPAC17G6.11c.1; -.
DR CAZy; GH16; Glycoside Hydrolase Family 16.
DR iPTMnet; O13789; -.
DR MaxQB; O13789; -.
DR PaxDb; O13789; -.
DR PRIDE; O13789; -.
DR EnsemblFungi; SPAC17G6.11c.1; SPAC17G6.11c.1:pep; SPAC17G6.11c.
DR GeneID; 2542171; -.
DR KEGG; spo:SPAC17G6.11c; -.
DR PomBase; SPAC17G6.11c; -.
DR VEuPathDB; FungiDB:SPAC17G6.11c; -.
DR eggNOG; ENOG502QR13; Eukaryota.
DR HOGENOM; CLU_010811_4_2_1; -.
DR InParanoid; O13789; -.
DR OMA; YITWINE; -.
DR PhylomeDB; O13789; -.
DR PRO; PR:O13789; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015926; F:glucosidase activity; IBA:GO_Central.
DR GO; GO:0006078; P:(1->6)-beta-D-glucan biosynthetic process; IBA:GO_Central.
DR GO; GO:0031505; P:fungal-type cell wall organization; IBA:GO_Central.
DR GO; GO:0030148; P:sphingolipid biosynthetic process; ISO:PomBase.
DR CDD; cd02180; GH16_fungal_KRE6_glucanase; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000757; GH16.
DR InterPro; IPR005629; Skn1/Kre6/Sbg1.
DR PANTHER; PTHR31361; PTHR31361; 1.
DR Pfam; PF03935; SKN1_KRE6_Sbg1; 1.
DR SUPFAM; SSF49899; SSF49899; 1.
DR PROSITE; PS51762; GH16_2; 1.
PE 3: Inferred from homology;
KW Cell wall biogenesis/degradation; Endoplasmic reticulum; Glycoprotein;
KW Membrane; Reference proteome; Signal-anchor; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..636
FT /note="Uncharacterized beta-glucan synthesis-associated
FT protein C17G6.11c"
FT /id="PRO_0000317219"
FT TOPO_DOM 1..170
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250|UniProtKB:P32486, ECO:0000255"
FT TRANSMEM 171..191
FT /note="Helical; Signal-anchor for type II membrane protein"
FT /evidence="ECO:0000255"
FT TOPO_DOM 192..636
FT /note="Lumenal"
FT /evidence="ECO:0000250|UniProtKB:P32486, ECO:0000255"
FT DOMAIN 218..587
FT /note="GH16"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01098"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 81..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 291
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 378
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 429
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 464
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 489
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 616
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 636 AA; 70008 MW; B30861820641323B CRC64;
MYNVRGDLNR KTPSDGNVNE IGSMYASRDT STSSFTNPTD SSTRLLYNNA SNATFSSAAL
AAGVGGTRAS GYTHRFSIRP SSQTYNRYPN GGNSAGSDMY STSPQNNSIV DDIENINKLE
AVAFAGPTAG ESDFSLSRED KEIDDFLHYP LPAKDAKKLS YFVGGEGLMQ LLFLLFLAAG
TGMLFIGLPI LTYTGHNSLA STRVTGITNH QFRILRLLRY GSLIDPDTPE SAYTFDSQDL
GTLDLVFSDE FNYPGRAFYD GDDQFWLATD LHYAATTDYE YYDADTPTTA NGTLRLRMDA
FYNHDLNFRS GMVTTWNKLC FKGGRIEVSA SLGGSPYIPG FWPGIWTIGN LVRPGYLATS
DGVWPYSYNS CDAGITPNQS DPSGISYLGG QRLNQCVCKG EDHPNVGTGR GGPEIDALEG
TFGSGIPYNG SIYLETMPVV SQSAQYAPFD LYMYPNYDFV TIYNQSVSAM NGWAGGVYQQ
ALSCASQLNN SWLSGNAYQK YGFDYKPGSG PDALISWFVG DEYTWTMRQP AVGQNGNIAS
RPVSEEPMIV VLNFGISPTW IYFYWYELTF PQTMYVDYVR IYQDSSDSSS VLGCDPEGFP
TTEYIANHPK AYLNYNATSW SEAGYVRPKN SLMDGC
