ID   CB60B_GOSHI             Reviewed;         576 AA.
AC   A0A1U8IPT1;
DT   23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2017, sequence version 1.
DT   03-AUG-2022, entry version 16.
DE   RecName: Full=Calmodulin-binding protein 60 B {ECO:0000303|PubMed:29757140};
DE   AltName: Full=GhCBP60B {ECO:0000303|PubMed:29757140};
GN   Name=CBP60B {ECO:0000303|PubMed:29757140};
GN   ORFNames=LOC107899061 {ECO:0000312|RefSeq:XP_016680151.1};
OS   Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX   NCBI_TaxID=3635 {ECO:0000312|Proteomes:UP000189702};
RN   [1] {ECO:0000312|Proteomes:UP000189702}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. TM-1 {ECO:0000312|Proteomes:UP000189702};
RX   PubMed=25893780; DOI=10.1038/nbt.3208;
RA   Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA   Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA   Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA   Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA   Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT   "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT   provides insights into genome evolution.";
RL   Nat. Biotechnol. 33:524-530(2015).
RN   [2] {ECO:0000305}
RP   FUNCTION, INTERACTION WITH V.DAHLIAE SCP41, AND SUBCELLULAR LOCATION.
RX   PubMed=29757140; DOI=10.7554/elife.34902;
RA   Qin J., Wang K., Sun L., Xing H., Wang S., Li L., Chen S., Guo H.S.,
RA   Zhang J.;
RT   "The plant-specific transcription factors CBP60g and SARD1 are targeted by
RT   a Verticillium secretory protein VdSCP41 to modulate immunity.";
RL   Elife 7:e34902-e34902(2018).
CC   -!- FUNCTION: Transcription activator that binds DNA in a sequence-specific
CC       manner, likely 5'-GAAATTTTGG-3', to promote the expression of target
CC       genes (By similarity). Required for pathogen resistance
CC       (PubMed:29757140). {ECO:0000250|UniProtKB:F4K2R6,
CC       ECO:0000269|PubMed:29757140}.
CC   -!- SUBUNIT: (Microbial infection) Interacts with V.dahliae SCP41.
CC       {ECO:0000269|PubMed:29757140}.
CC   -!- SUBUNIT: Interacts with calmodulin (CaM).
CC       {ECO:0000250|UniProtKB:F4K2R6}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:29757140}.
CC   -!- SIMILARITY: Belongs to the plant ACBP60 protein family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_016680151.1; XM_016824662.1.
DR   STRING; 3635.A0A1U8IPT1; -.
DR   GeneID; 107899061; -.
DR   KEGG; ghi:107899061; -.
DR   OMA; CGEIRIR; -.
DR   Proteomes; UP000189702; Chromosome 17.
DR   GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR   GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0098542; P:defense response to other organism; IMP:UniProtKB.
DR   GO; GO:0080142; P:regulation of salicylic acid biosynthetic process; IBA:GO_Central.
DR   InterPro; IPR012416; CBP60.
DR   PANTHER; PTHR31713; PTHR31713; 1.
DR   Pfam; PF07887; Calmodulin_bind; 1.
PE   1: Evidence at protein level;
KW   Activator; Calmodulin-binding; DNA-binding; Nucleus; Plant defense;
KW   Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..576
FT                   /note="Calmodulin-binding protein 60 B"
FT                   /id="PRO_0000454500"
FT   REGION          1..80
FT                   /note="Calmodulin-binding"
FT                   /evidence="ECO:0000250|UniProtKB:F4K2R6"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          150..273
FT                   /note="DNA-binding"
FT                   /evidence="ECO:0000250|UniProtKB:F4K2R6"
FT   COMPBIAS        8..25
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   576 AA;  65173 MW;  A14F2DC37E30BBE7 CRC64;
     MMLPTKRPAP DHGDDERNEV MVPEPKRRTN LKKNIMGVGG LSFNKIVLNL EPMLRIWVHE
     AVEAAIRSSI HPSSRPSLNR IEASRGRRLQ LRFVDKPPST IFTGSKVEAE NGNPIRIILV
     DATSQAMVSS GSLSSIKVEI VVLNGEFGTD ERQDWTENEF NASVLREREG RRPLVTGDLN
     ITLVDGVGTV DNVIFTDNSS WIRCRKFRLG ARIVQRSAGE VTIREATSDA FMVKDHRGEL
     YKKHYPPLLH DEVWRLERIA KDGAFHKRLA YKNVHTVKDF LRLLVTDPIA LRNILGGGIS
     NRVWETIIEH ALSCVPDDDE WYTYHGTAQR VELLLNSIYN VVKVTFDGQD YLPVENLTFS
     QKLLVEDAKR QAYKNVWNLT PFDRRAIMGP SMPFTDLLPE PVGTSNLLLQ QHDFSGTRPD
     MPLGLNQSST SFSYEVENPK PLQGIEPLNP MLRNSSFRME GIFPYNADNS FSFFADDGFG
     TNQDNTQAQM LSLTSATPAW AQGSGFIFTP DYETSSISFL SSFPSCNVND RSIGETREVC
     PKNRWLKVRA VIQWKSISRG AAKRRRQHWL QHGICT