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YERA_YERE8
ID   YERA_YERE8              Reviewed;         130 AA.
AC   P31490; A1JUA8;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=YopE regulator;
GN   Name=yerA; OrderedLocusNames=YEP0052;
OS   Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 /
OS   8081).
OG   Plasmid pYVe8081.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=393305;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2307658; DOI=10.1128/jb.172.3.1547-1555.1990;
RA   Forsberg A., Wolf-Watz H.;
RT   "Genetic analysis of the yopE region of Yersinia spp.: identification of a
RT   novel conserved locus, yerA, regulating yopE expression.";
RL   J. Bacteriol. 172:1547-1555(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 13174 / 8081;
RX   PubMed=17173484; DOI=10.1371/journal.pgen.0020206;
RA   Thomson N.R., Howard S., Wren B.W., Holden M.T.G., Crossman L.,
RA   Challis G.L., Churcher C., Mungall K., Brooks K., Chillingworth T.,
RA   Feltwell T., Abdellah Z., Hauser H., Jagels K., Maddison M., Moule S.,
RA   Sanders M., Whitehead S., Quail M.A., Dougan G., Parkhill J.,
RA   Prentice M.B.;
RT   "The complete genome sequence and comparative genome analysis of the high
RT   pathogenicity Yersinia enterocolitica strain 8081.";
RL   PLoS Genet. 2:2039-2051(2006).
CC   -!- FUNCTION: Positive regulator of YopE.
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DR   EMBL; M34278; AAA27673.1; -; Genomic_DNA.
DR   EMBL; AM286416; CAL10074.1; -; Genomic_DNA.
DR   RefSeq; NP_783701.1; NC_004564.1.
DR   RefSeq; NP_863548.1; NC_005017.1.
DR   RefSeq; WP_005176499.1; NC_008791.1.
DR   RefSeq; YP_001004104.1; NC_008791.1.
DR   PDB; 1N5B; X-ray; 2.00 A; A/B/C/D=1-130.
DR   PDBsum; 1N5B; -.
DR   AlphaFoldDB; P31490; -.
DR   BMRB; P31490; -.
DR   SMR; P31490; -.
DR   STRING; 393305.YEP0052; -.
DR   EnsemblBacteria; CAL10074; CAL10074; YEP0052.
DR   KEGG; yen:YEP0052; -.
DR   PATRIC; fig|393305.7.peg.53; -.
DR   eggNOG; ENOG50332A3; Bacteria.
DR   HOGENOM; CLU_159406_0_0_6; -.
DR   OMA; LFSQDPC; -.
DR   EvolutionaryTrace; P31490; -.
DR   PRO; PR:P31490; -.
DR   Proteomes; UP000000642; Plasmid pYVe8081.
DR   GO; GO:0030254; P:protein secretion by the type III secretion system; IEA:InterPro.
DR   InterPro; IPR005416; T3SS_chp_SycE.
DR   InterPro; IPR010261; Tir_chaperone.
DR   Pfam; PF05932; CesT; 1.
DR   PIRSF; PIRSF011271; T3SS_chp_SycE_GmN_bac; 1.
DR   PRINTS; PR01596; SYCECHAPRONE.
PE   1: Evidence at protein level;
KW   3D-structure; Activator; Plasmid; Transcription; Transcription regulation;
KW   Virulence.
FT   CHAIN           1..130
FT                   /note="YopE regulator"
FT                   /id="PRO_0000066202"
FT   HELIX           5..14
FT                   /evidence="ECO:0007829|PDB:1N5B"
FT   STRAND          25..31
FT                   /evidence="ECO:0007829|PDB:1N5B"
FT   STRAND          34..40
FT                   /evidence="ECO:0007829|PDB:1N5B"
FT   STRAND          45..50
FT                   /evidence="ECO:0007829|PDB:1N5B"
FT   HELIX           60..65
FT                   /evidence="ECO:0007829|PDB:1N5B"
FT   STRAND          77..81
FT                   /evidence="ECO:0007829|PDB:1N5B"
FT   TURN            82..85
FT                   /evidence="ECO:0007829|PDB:1N5B"
FT   STRAND          86..94
FT                   /evidence="ECO:0007829|PDB:1N5B"
FT   HELIX           102..117
FT                   /evidence="ECO:0007829|PDB:1N5B"
SQ   SEQUENCE   130 AA;  14676 MW;  491B67B4C293CA5A CRC64;
     MYSFEQAITQ LFQQLSLSIP DTIEPVIGVK VGEFACHITE HPVGQILMFT LPSLDNNNEK
     ETLLSHNIFS QDILKPILSW DEVGGHPVLW NRQPLNNLDN NSLYTQLEML VQGAERLQTS
     SLISPPRSFS
 
 
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