ID   YERD_BACSU              Reviewed;         525 AA.
AC   O34849; O30568; Q799E7;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Glutamate synthase large subunit-like protein YerD;
GN   Name=yerD; Synonyms=yecE; OrderedLocusNames=BSU06590;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9701819; DOI=10.1046/j.1365-2958.1998.00927.x;
RA   Petit M.-A., Dervyn E., Rose M., Entian K.-D., McGovern S., Ehrlich S.D.,
RA   Bruand C.;
RT   "PcrA is an essential DNA helicase of Bacillus subtilis fulfilling
RT   functions both in repair and rolling-circle replication.";
RL   Mol. Microbiol. 29:261-273(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 317-525.
RC   STRAIN=168;
RX   PubMed=8969499; DOI=10.1099/13500872-142-11-3027;
RA   Borriss R., Porwollik S., Schroeter R.;
RT   "The 52 degrees-55 degrees segment of the Bacillus subtilis chromosome: a
RT   region devoted to purine uptake and metabolism, and containing the genes
RT   cotA, gabP and guaA and the pur gene cluster within a 34960 bp nucleotide
RT   sequence.";
RL   Microbiology 142:3027-3031(1996).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the glutamate synthase family. {ECO:0000305}.
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DR   EMBL; Y15254; CAA75550.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12479.1; -; Genomic_DNA.
DR   EMBL; AF011544; AAB72191.1; -; Genomic_DNA.
DR   PIR; C69794; C69794.
DR   RefSeq; NP_388541.1; NC_000964.3.
DR   RefSeq; WP_003233925.1; NZ_JNCM01000032.1.
DR   AlphaFoldDB; O34849; -.
DR   SMR; O34849; -.
DR   STRING; 224308.BSU06590; -.
DR   PaxDb; O34849; -.
DR   PRIDE; O34849; -.
DR   EnsemblBacteria; CAB12479; CAB12479; BSU_06590.
DR   GeneID; 936058; -.
DR   KEGG; bsu:BSU06590; -.
DR   PATRIC; fig|224308.179.peg.716; -.
DR   eggNOG; COG0069; Bacteria.
DR   InParanoid; O34849; -.
DR   OMA; CIGHPWE; -.
DR   PhylomeDB; O34849; -.
DR   BioCyc; BSUB:BSU06590-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015930; F:glutamate synthase activity; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IBA:GO_Central.
DR   GO; GO:0006537; P:glutamate biosynthetic process; IEA:InterPro.
DR   CDD; cd02808; GltS_FMN; 1.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR024188; GltB.
DR   InterPro; IPR002932; Glu_synthdom.
DR   InterPro; IPR027283; YerD.
DR   Pfam; PF01645; Glu_synthase; 1.
DR   PIRSF; PIRSF006429; GOGAT_lg_2; 1.
DR   PIRSF; PIRSF500060; UCP500060; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..525
FT                   /note="Glutamate synthase large subunit-like protein YerD"
FT                   /id="PRO_0000388342"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   525 AA;  58752 MW;  05DA800E1590F8C2 CRC64;
     METIIIALIA FIIGIIAIPI VLFAWIYIKD EKQQEHSILR NYPVIGRFRY ILEKIGPELR
     QYLYSNDNEE QPFSRKEYEQ TVISGKYKSR MMGFGSVRDF DKPGYYIRNA MFPKQREEMH
     VNQTPKIETQ IYKMDADNLF KRKEHAEHIK ADPYFLHPDD VQVIGEHTCE KPFYVKGLVG
     QSAMSYGSLG ERAVTALSKG LHLAGGTWMN TGEGGLSEYH LKGGADIICQ IGPGLFGVRK
     RNGEFSWEEF KRKSRIDQIK AFELKLAQGA KTRGGHVDGA KVSEEVADIR NVEPGKSIDS
     PNRFYEFSNP PEMLDFIEKL RDVGQKPVGI KLVAGHPEEL HELFSHMQKS GKHPDFITID
     GSEGGTGASF YELADTVGLP IMTALPIVDT LLKQYGLRSQ LKIFASGKLL TPDKIAVALA
     LGADFVNIAR GMMFSVGCIR ALVCHTNTCP AGVATTDPKL QKALSVEEKQ HRVCNYVISL
     REGLFNLAAA AGINSPIHFS KEHVVYRKED GSIINIDNLI HQFVS