ID   YERH_BACSU              Reviewed;         396 AA.
AC   O34629; Q799E6;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Uncharacterized lipoprotein YerH;
DE   Flags: Precursor;
GN   Name=yerH; OrderedLocusNames=BSU06630;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9701819; DOI=10.1046/j.1365-2958.1998.00927.x;
RA   Petit M.-A., Dervyn E., Rose M., Entian K.-D., McGovern S., Ehrlich S.D.,
RA   Bruand C.;
RT   "PcrA is an essential DNA helicase of Bacillus subtilis fulfilling
RT   functions both in repair and rolling-circle replication.";
RL   Mol. Microbiol. 29:261-273(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION.
RC   STRAIN=168 / Marburg / ATCC 6051 / DSM 10 / JCM 1465 / NBRC 13719 / NCIMB
RC   3610 / NRRL NRS-744 / VKM B-501;
RX   PubMed=22882210; DOI=10.1111/j.1365-2958.2012.08205.x;
RA   Yepes A., Schneider J., Mielich B., Koch G., Garcia-Betancur J.C.,
RA   Ramamurthi K.S., Vlamakis H., Lopez D.;
RT   "The biofilm formation defect of a Bacillus subtilis flotillin-defective
RT   mutant involves the protease FtsH.";
RL   Mol. Microbiol. 86:457-471(2012).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303, ECO:0000269|PubMed:22882210}; Lipid-anchor
CC       {ECO:0000255|PROSITE-ProRule:PRU00303}. Membrane raft
CC       {ECO:0000269|PubMed:22882210}. Note=Present in detergent-resistant
CC       membrane (DRM) fractions that may be equivalent to eukaryotic membrane
CC       rafts; these rafts include proteins involved in signaling, molecule
CC       trafficking and protein secretion. {ECO:0000269|PubMed:22882210}.
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DR   EMBL; Y15254; CAA75553.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12483.1; -; Genomic_DNA.
DR   PIR; G69794; G69794.
DR   RefSeq; NP_388545.1; NC_000964.3.
DR   RefSeq; WP_003242795.1; NZ_JNCM01000032.1.
DR   AlphaFoldDB; O34629; -.
DR   SMR; O34629; -.
DR   STRING; 224308.BSU06630; -.
DR   jPOST; O34629; -.
DR   PaxDb; O34629; -.
DR   PRIDE; O34629; -.
DR   DNASU; 938744; -.
DR   EnsemblBacteria; CAB12483; CAB12483; BSU_06630.
DR   GeneID; 938744; -.
DR   KEGG; bsu:BSU06630; -.
DR   PATRIC; fig|224308.179.peg.721; -.
DR   eggNOG; COG4851; Bacteria.
DR   OMA; YQKEQYG; -.
DR   PhylomeDB; O34629; -.
DR   BioCyc; BSUB:BSU06630-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR011426; CamS.
DR   Pfam; PF07537; CamS; 1.
DR   PIRSF; PIRSF012509; CamS; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           19..396
FT                   /note="Uncharacterized lipoprotein YerH"
FT                   /id="PRO_0000360735"
FT   REGION          126..155
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        140..155
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           19
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           19
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   396 AA;  44517 MW;  BEDA50C1A0DA892E CRC64;
     MKKTLALAAT AAVLMLSACS SGFGGEKEEE ITQKTAKSSE KAIVPKYNIS DSYYKMVLPF
     KAGKARGLTT EQLNTRLDID EFETGLMRLA QDSFSTDDYL FQEGQYLDED TVLSWLARKK
     TGSDLKKAEK EDKNFKNEGL NPALPSSGST EEKNESSPIY LASMLEHDYL VRKDKNSIQL
     GGVMIGLALN SVYYYREKTG DPQKEVEIKD STLRQQGEKI AQEVINRLRK KDNLKNVPIT
     VALYKQASKT SIVPGNFIAK TEVKAGSTDI SNWDDINEKY VFYPADTTTA EKYPDDTEVF
     KRFKNSIEEY FPNYTGVVGT ALYENDEMKK MKIDIPMQFY GKSEVVAFTQ FLTGEVMDYY
     SKSSVDVEVN ITSSDGQEAV IIRNAGDKEP TVHIYD