YESS_BACSU
ID YESS_BACSU Reviewed; 761 AA.
AC O31522;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=HTH-type transcriptional regulator YesS;
GN Name=yesS; OrderedLocusNames=BSU07010;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [2]
RP INDUCTION, AND PROBABLE FUNCTION.
RX PubMed=17449691; DOI=10.1128/aem.00147-07;
RA Ochiai A., Itoh T., Kawamata A., Hashimoto W., Murata K.;
RT "Plant cell wall degradation by saprophytic Bacillus subtilis strains: gene
RT clusters responsible for rhamnogalacturonan depolymerization.";
RL Appl. Environ. Microbiol. 73:3803-3813(2007).
CC -!- FUNCTION: Probable transcription factor regulating the pathway
CC responsible for rhamnogalacturonan depolymerization.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- INDUCTION: By rhamnogalacturonan type I (RG-I), a component of pectin
CC from the plant cell wall. {ECO:0000269|PubMed:17449691}.
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DR EMBL; AL009126; CAB12520.1; -; Genomic_DNA.
DR PIR; B69797; B69797.
DR RefSeq; NP_388582.1; NC_000964.3.
DR RefSeq; WP_009966769.1; NZ_JNCM01000032.1.
DR AlphaFoldDB; O31522; -.
DR SMR; O31522; -.
DR IntAct; O31522; 19.
DR STRING; 224308.BSU07010; -.
DR PaxDb; O31522; -.
DR PRIDE; O31522; -.
DR EnsemblBacteria; CAB12520; CAB12520; BSU_07010.
DR GeneID; 936075; -.
DR KEGG; bsu:BSU07010; -.
DR PATRIC; fig|224308.179.peg.761; -.
DR eggNOG; COG2207; Bacteria.
DR OMA; KKIHDVS; -.
DR PhylomeDB; O31522; -.
DR BioCyc; BSUB:BSU07010-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR018062; HTH_AraC-typ_CS.
DR Pfam; PF12833; HTH_18; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SUPFAM; SSF46689; SSF46689; 2.
DR PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; DNA-binding; Membrane; Reference proteome; Transcription;
KW Transcription regulation; Transmembrane; Transmembrane helix.
FT CHAIN 1..761
FT /note="HTH-type transcriptional regulator YesS"
FT /id="PRO_0000360792"
FT TOPO_DOM 1..22
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 23..43
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 44..285
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 286..306
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 307..761
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 659..756
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT DNA_BIND 676..697
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
SQ SEQUENCE 761 AA; 87749 MW; C05ACB00F020CC3D CRC64;
MKKQPQQKER VSRWKGTYFK RNFVFILLIA CIPGLLTGGA IYFLSIDKVE KELQRSHETQ
VAREVSRMDE KLGVLELALT QMAYDSSLMN GLAERDLEKD FTFSYQLTKK LFLLRDQQPL
IEQASIFLNS PRPLVLSPEY SALTEQEALR KYRSLLASDH SIYWKRSGNQ AMLIQLIPGA
AEKPFGAIML AVDPKEMESI LQSLSPYPDG SALLLDQNRE VLFHEGEKDF EKTLLHEIKK
QPAENGHFQM EWKGKVYSVS FGEMNRMHQQ WTFVSAAPLS AITAPMVFLS KVIIVMLVIC
IGLAVCMTWY ASKKIYRPIQ HLLGLFTGGE KKTWQASGQD EFKWIEKRWQ DLSLESRKLQ
QQLLRQTPHM KKSFLQHLLQ SDFYYDNEES LRFRMEEAGW NIGGNVFHVL DLQVTGLRCE
KSIFREGDEQ LAVFTLTNIA EELAAKRVFQ LSILDIGRLS VTVLVMKTNS SDLKAYITEL
ARQFGDVTGL CLTSTLSSKT ERVTEIPSLF QDVKCGKSRR KFANRDQVID LQADFPRDEQ
FAPYYPFELE KQIVQTIRLE RKQEAKELID GCMKELSEKA AIDRHVHSAL IQLFSRIQED
ILHSGLNPSE LFQHRNPFLD ISELREPNEA AAWLMDVVVT PYLSKLEGRK NRQQKQLAER
VIAMIHEQYM ADISLESCAD ALGMNSYTLS KAFKQVTGIN FIDYVTQIRI EKAKELLVNT
NKKIHDVSEE VGYRHNYFNR IFKKQVGMPP GVFRQMYQET P
