YETL_DICDI
ID YETL_DICDI Reviewed; 206 AA.
AC Q54K74;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 08-APR-2008, sequence version 2.
DT 25-MAY-2022, entry version 71.
DE RecName: Full=Endoplasmic reticulum transmembrane protein YET-like;
GN ORFNames=DDB_G0287543;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- FUNCTION: May play a role in anterograde transport of membrane proteins
CC from the endoplasmic reticulum to the Golgi.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the BCAP29/BCAP31 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EAL63671.2; Type=Erroneous gene model prediction; Note=Genome sequence is incorrect in N-terminal but ESTs confirm our prediction.; Evidence={ECO:0000305};
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DR EMBL; AAFI02000102; EAL63671.2; ALT_SEQ; Genomic_DNA.
DR RefSeq; XP_637181.2; XM_632089.2.
DR AlphaFoldDB; Q54K74; -.
DR SMR; Q54K74; -.
DR STRING; 44689.DDB0266343; -.
DR PaxDb; Q54K74; -.
DR EnsemblProtists; EAL63671; EAL63671; DDB_G0287543.
DR GeneID; 8626182; -.
DR KEGG; ddi:DDB_G0287543; -.
DR dictyBase; DDB_G0287543; -.
DR eggNOG; KOG1962; Eukaryota.
DR InParanoid; Q54K74; -.
DR PhylomeDB; Q54K74; -.
DR Reactome; R-DDI-75153; Apoptotic execution phase.
DR PRO; PR:Q54K74; -.
DR Proteomes; UP000002195; Chromosome 5.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0070973; P:protein localization to endoplasmic reticulum exit site; IBA:GO_Central.
DR InterPro; IPR008417; BAP29/BAP31.
DR InterPro; IPR040463; BAP29/BAP31_N.
DR InterPro; IPR041672; Bap31/Bap29_C.
DR PANTHER; PTHR12701; PTHR12701; 1.
DR Pfam; PF05529; Bap31; 1.
DR Pfam; PF18035; Bap31_Bap29_C; 1.
PE 3: Inferred from homology;
KW Coiled coil; Endoplasmic reticulum; ER-Golgi transport; Membrane;
KW Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..206
FT /note="Endoplasmic reticulum transmembrane protein YET-
FT like"
FT /id="PRO_0000327213"
FT TOPO_DOM 1..2
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 24..46
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 68..101
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 102..122
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 123..206
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT COILED 140..198
FT /evidence="ECO:0000255"
FT MOTIF 203..206
FT /note="Di-lysine motif"
SQ SEQUENCE 206 AA; 24193 MW; 3983AE71A31D3ABD CRC64;
MEFLMTLVFL VLLVEIVFCT FFMLPVSMHL RKNVYNKLDK LFGGQNAKIF LKVLALLVII
VFCDSIVNSY NINKKLHTPE LTGAKFDRQN EYTRMFRYQR NSYICGFCLY LFFLIYRSQG
IISQLSNVEA SKTAIEKQTK NNLNTVETLL SENEKLKTEI KDLKKMEKEH KAMKSQAENT
TKEYLKLQEE YNQLLGKKPK TQKKDD
