ID   YEU5_SCHPO              Reviewed;         363 AA.
AC   O13704;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 2.
DT   25-MAY-2022, entry version 132.
DE   RecName: Full=Thioredoxin domain-containing protein C13F5.05, mitochondrial;
DE   Flags: Precursor;
GN   ORFNames=SPAC13F5.05;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:16823372}.
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DR   EMBL; CU329670; CAB11768.2; -; Genomic_DNA.
DR   PIR; T37630; T37630.
DR   RefSeq; NP_593653.1; NM_001019085.2.
DR   AlphaFoldDB; O13704; -.
DR   SMR; O13704; -.
DR   BioGRID; 279287; 3.
DR   STRING; 4896.SPAC13F5.05.1; -.
DR   MaxQB; O13704; -.
DR   PaxDb; O13704; -.
DR   EnsemblFungi; SPAC13F5.05.1; SPAC13F5.05.1:pep; SPAC13F5.05.
DR   GeneID; 2542841; -.
DR   KEGG; spo:SPAC13F5.05; -.
DR   PomBase; SPAC13F5.05; -.
DR   VEuPathDB; FungiDB:SPAC13F5.05; -.
DR   eggNOG; KOG0191; Eukaryota.
DR   HOGENOM; CLU_765385_0_0_1; -.
DR   InParanoid; O13704; -.
DR   OMA; YLDSFCT; -.
DR   PhylomeDB; O13704; -.
DR   PRO; PR:O13704; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005788; C:endoplasmic reticulum lumen; NAS:PomBase.
DR   GO; GO:0005739; C:mitochondrion; HDA:PomBase.
DR   GO; GO:0003756; F:protein disulfide isomerase activity; ISO:PomBase.
DR   GO; GO:0015035; F:protein-disulfide reductase activity; ISO:PomBase.
DR   GO; GO:0034975; P:protein folding in endoplasmic reticulum; IC:PomBase.
DR   InterPro; IPR044569; PDIA6-like.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR017937; Thioredoxin_CS.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   PANTHER; PTHR45815; PTHR45815; 1.
DR   Pfam; PF00085; Thioredoxin; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   PROSITE; PS00194; THIOREDOXIN_1; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   4: Predicted;
KW   Mitochondrion; Reference proteome; Transit peptide.
FT   TRANSIT         1..24
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..363
FT                   /note="Thioredoxin domain-containing protein C13F5.05,
FT                   mitochondrial"
FT                   /id="PRO_0000303924"
FT   DOMAIN          32..141
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
SQ   SEQUENCE   363 AA;  40764 MW;  ED3778260EC955A1 CRC64;
     MLFRIPTLFT LFLACFSLVS GVFGYSPMFG SNTIELNSKN FRKFVKAKGP SLVVFYAPWC
     GYCKKLVPTY QKLASNLHSL LPVTAVDCDA DQNRAVCSQY QVQGFPTIKL VYPSSKGSSL
     SSTDYNGDRS YKSLQKFVSD SIPSKVKILT SEAKTQKFIQ DAQNSSKVIL ISQKMKPTLL
     YKSLSNEFSS LPFSFMPAKA NVNDLFNISA YVDTSDLPIL FIKHPNNGTS FFSNSLNRDS
     IVEFLQSSIK DNNFSEYLAT FCSKKSCIIT IQDKDSDSGI DESIRKKYPK LHFVRLGRNT
     TVAERLEDTL DLGYSDTFLL SLKKSHYNAK PYGKPLRRWL EDIQVQQAGP SVSLPNDLLS
     KIK