YEY8_YEAST
ID YEY8_YEAST Reviewed; 573 AA.
AC P40095; D3DM65;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1995, sequence version 1.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Uncharacterized protein YER158C;
GN OrderedLocusNames=YER158C;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169868;
RA Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E.,
RA Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E.,
RA Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S.,
RA Hyman R.W., Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D.,
RA Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X.,
RA Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y.,
RA Botstein D., Davis R.W.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome V.";
RL Nature 387:78-81(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [4]
RP GLYCOSYLATION [LARGE SCALE ANALYSIS].
RX PubMed=19756047; DOI=10.1038/msb.2009.64;
RA Kung L.A., Tao S.-C., Qian J., Smith M.G., Snyder M., Zhu H.;
RT "Global analysis of the glycoproteome in Saccharomyces cerevisiae reveals
RT new roles for protein glycosylation in eukaryotes.";
RL Mol. Syst. Biol. 5:308-308(2009).
CC -!- INTERACTION:
CC P40095; P38041: BOI1; NbExp=4; IntAct=EBI-22734, EBI-3719;
CC P40095; P39969: BOI2; NbExp=3; IntAct=EBI-22734, EBI-3727;
CC -!- PTM: N-glycosylated. {ECO:0000269|PubMed:19756047}.
CC -!- MISCELLANEOUS: Present with 784 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
CC -!- SIMILARITY: To yeast AFR1. {ECO:0000305}.
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DR EMBL; U18917; AAB64685.1; -; Genomic_DNA.
DR EMBL; BK006939; DAA07819.1; -; Genomic_DNA.
DR PIR; S50661; S50661.
DR RefSeq; NP_011085.1; NM_001179048.1.
DR AlphaFoldDB; P40095; -.
DR BioGRID; 36909; 41.
DR DIP; DIP-2686N; -.
DR IntAct; P40095; 7.
DR MINT; P40095; -.
DR STRING; 4932.YER158C; -.
DR iPTMnet; P40095; -.
DR PaxDb; P40095; -.
DR PRIDE; P40095; -.
DR EnsemblFungi; YER158C_mRNA; YER158C; YER158C.
DR GeneID; 856903; -.
DR KEGG; sce:YER158C; -.
DR SGD; S000000960; YER158C.
DR VEuPathDB; FungiDB:YER158C; -.
DR eggNOG; ENOG502TFUM; Eukaryota.
DR HOGENOM; CLU_486751_0_0_1; -.
DR InParanoid; P40095; -.
DR OMA; FADEIYV; -.
DR BioCyc; YEAST:G3O-30319-MON; -.
DR PRO; PR:P40095; -.
DR Proteomes; UP000002311; Chromosome V.
DR RNAct; P40095; protein.
DR GO; GO:0003779; F:actin binding; IBA:GO_Central.
DR GO; GO:0030036; P:actin cytoskeleton organization; IBA:GO_Central.
PE 1: Evidence at protein level;
KW Glycoprotein; Reference proteome; Repeat.
FT CHAIN 1..573
FT /note="Uncharacterized protein YER158C"
FT /id="PRO_0000202656"
FT REPEAT 102..103
FT /note="1"
FT REPEAT 104..105
FT /note="2"
FT REPEAT 106..107
FT /note="3"
FT REPEAT 108..109
FT /note="4"
FT REPEAT 110..111
FT /note="5"
FT REPEAT 112..113
FT /note="6"
FT REPEAT 114..115
FT /note="7"
FT REPEAT 116..117
FT /note="8"
FT REPEAT 118..119
FT /note="9"
FT REPEAT 120..121
FT /note="10"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 60..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 102..121
FT /note="10 X 2 AA tandem repeats of N-M"
FT REGION 150..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 192..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 286..317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 357..379
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 441..483
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..174
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 296..310
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 63
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 123
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 236
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 437
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 442
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 498
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 535
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 541
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 573 AA; 63712 MW; 7D24F55CF5CFCA4D CRC64;
MLQQGSSSRR SLHGNDFHTL TSPSRRDSLS IPRAVDARSA STIDLFYIPD ATVSRRHSTL
VANRSDNNGN GAPMRQYNKP NFASSSTSSL PSTRNRPSRY DNMNMNMNMN MNMNMNMNMN
MNNHTTSDHN AHPQYRCRPN PSRRHSLMTI PEKYSGSRYS LRSSPPTYSN PRVRKELTPF
QLQRKQMKSA FQFPNGENFT PRNQIARLPP SSTFPDSPSS SSLPLTQTGG PSSADNDSIA
TGTNNRSPQQ TKAADANQKS ESESPKAIRS NSKKISRFFR KIWSSKSSNS ADSVEENSKT
KQKRKNPERV VPEPITSLDQ PVEIIKQSFS TVNNHETAVP SIKDSGIVQE LTALGDNNRI
PVLPPPRSPN RPTLSDKRTT KLYYCSQDSS NEDIAPEEKS TVFLKRLQDE WSTVYLNKLP
LTASVPSSLS TTTDAANSSF INSSISSPAP SSSSSSSLVS RGPMQSISSS PTPAPSSGSS
KSKNAVKSLR FADEIYVNDT WSAADYCRCD NTFLNNFFKG KSQDITNPST FVGNNLSSTK
NISNIEIKME VNEFKRKEMR VHQDSAKYTH YYL
